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    Glossary Type I Collagen

    most abundant protein in skin, bones, and tendons

    Type I Collagen is the most abundant collagen in the human body, making up about 90% of the collagen found in skin, bones, tendons, and other connective tissues. It provides structural support and strength, playing a crucial role in wound healing and maintaining the integrity of various tissues.

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    1. Collagenase IV plays an important role in regulating hair cycle by inducing VEGF, IGF-1, and TGF-β expression Drug Design Development and Therapy · 2015 · 27 citations
    2. Collagenase IV plays an important role in regulating hair cycle by inducing VEGF, IGF-1, and TGF-β expression. PubMed · 2015 · 26 citations
    3. Growth factors specifically alter hair follicle cell proliferation and collagenolytic activity alone or in combination Differentiation · 1990 · 56 citations
    4. Expression of extracellular matrix in hair follicle mesenchyme in alopecia areata British Journal of Dermatology · 1990 · 11 citations
    5. Expression of the Orphan Protein Plet-1 during Trichilemmal Differentiation of Anagen Hair Follicles 2010 · 30 citations
    6. Matrix Metalloproteinase-19 Expression in Normal and Diseased Skin: Dysregulation by Epidermal Proliferation Journal of Investigative Dermatology · 2003 · 56 citations
    7. Correlation of proteolytic activities of organ cultured intact mouse skin with defined hair cycle stages Journal of Dermatological Science · 1994 · 28 citations
    8. Screening and culture of human vaginal mucosa stem cells Zhongguo zuzhi gongcheng yanjiu yu linchuang kangfu · 2008
    9. The distributions of type IV collagen .ALPHA. chains in basement membranes of human epidermis and skin appendages Archives of Histology and Cytology · 2007 · 36 citations
    10. Effects of extracellular matrix on the growth characteristics of human dermal papillae cells<i>in vitro</i> Clinical and Experimental Dermatology · 2016 · 2 citations
    11. [Experimental study on vascular endothelial growth factor 165 gene-modified rat hair follicle stem cells mediated by lentiviral vector]. PubMed · 2014
    12. A New Approach with Combined Microneedle and Sublative Fractional Radiofrequency for Photoaging Management: A Clinical, Histometric, and Immunohistochemical Study Aesthetic Plastic Surgery · 2024 · 4 citations
    13. Evidence-Based and Potential Benefits of Metformin in the Polycystic Ovary Syndrome: A Comprehensive Review Endocrine Reviews · 2008 · 343 citations
    14. Rice bran mineral extract increases the expression of anagen-related molecules in human dermal papilla through wnt/catenin pathway Food & Nutrition Research · 2017 · 9 citations
    15. Pathophysiology of the burn scar Elsevier eBooks · 2012 · 3 citations
    16. Protective Mechanism of Adipose-Derived Stem Cells in Remodelling of the Skin Stem Cell Niche During Photoaging Cellular Physiology and Biochemistry · 2018 · 13 citations
    17. Chromolaena odorata layered-nitrile rubber polymer transdermal patch enhanced wound healing in vivo PloS one · 2024
    18. The enhancement of dermal papilla cell aggregation by extracellular matrix proteins through effects on cell–substratum adhesivity and cell motility Biomaterials · 2009 · 44 citations
    19. Skin-permeable liposome improved stability and permeability of bFGF against skin of mice with deep second degree scald to promote hair follicle neogenesis through inhibition of scar formation Colloids and Surfaces B: Biointerfaces · 2018 · 26 citations
    20. Unravelling the link between insulin resistance and androgen excess University of Birmingham Institutional Research Archive (University of Birmingham) · 2015
    21. Fibroproliferative genes are preferentially expressed in central centrifugal cicatricial alopecia Journal of The American Academy of Dermatology · 2018 · 25 citations
    22. Structures of three polycystic kidney disease-like domains from<i>Clostridium histolyticum</i>collagenases ColG and ColH Acta Crystallographica Section D: Structural Biology · 2015 · 18 citations
    23. Basement Membrane Zone Remodeling During Appendageal Development in Human Fetal Skin. The Absence of Type VII Collagen is Associated with Gelatinase-A (MMP2) Activity Journal of Investigative Dermatology · 2000 · 42 citations
    24. Histological and molecular restoration of type VII collagen in Recessive dystrophic epidermolysis bullosa mouse skin by topical injection of keratinocyte-like cells differentiated from human adipose-derived mesenchymal stromal cells Journal of Dermatological Science · 2024 · 1 citations
    25. Synergistic Effects of Fractional CO <sub>2</sub> Laser and Recombinant Humanized Type III Collagen (rhCol III) in Atrophic Acne Scar Treatment: Activation of MAPK Pathway and Enhanced Collagen Remodeling Dermatologic Therapy · 2025
    26. Skin-type-dependent development of murine mechanosensory neurons Developmental Cell · 2023 · 13 citations
    27. Type XVII collagen coordinates proliferation in the interfollicular epidermis eLife · 2017 · 124 citations
    28. Cell Type-specific Functions of the Lysosomal Protease Cathepsin L in the Heart Journal of Biological Chemistry · 2007 · 56 citations
    29. Mesenchymal Stem Cells from Mouse Hair Follicles Inhibit the Development of Type 1 Diabetes International Journal of Molecular Sciences · 2024
    30. Immunofluorescent localization of collagen types I, III and IV, fibronectin, laminin, and basement membrane proteoglycan in developing mouse skin Development Genes and Evolution · 1987 · 20 citations