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    Glossary Type I Interferons

    proteins that help the immune system fight viral infections

    Type I Interferons (Type I IFNs) are a group of proteins that play a crucial role in the body's immune response to viral infections. They help to inhibit viral replication within host cells and activate immune cells, such as natural killer cells and macrophages, to fight off the infection. These proteins are also involved in regulating the immune system and can influence the development of autoimmune conditions.

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    1. The use of oral recombinant feline interferon omega in two cats with type II diabetes mellitus and concurrent feline chronic gingivostomatitis syndrome Irish Veterinary Journal · 2013 · 16 citations
    2. 431 Innate lymphoid cells type 1 may be new, non-antigen-specific player in the pathogenesis of alopecia areata Journal of Investigative Dermatology · 2019
    3. Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing Frontiers in Immunology · 2024 · 7 citations
    4. Comment on: The Gabrin sign Journal of The American Academy of Dermatology · 2020 · 3 citations
    5. Cutaneous Manifestations in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED): A Comprehensive Review Biomedicines · 2024
    6. Relationships between hair-follicle afferent axons and glycine-immunoreactive profiles in cat spinal dorsal horn Brain Research · 1991 · 31 citations
    7. 516 Possible role of ILC1 in the pathogenesis of alopecia areata (AA) 2019 · 3 citations
    8. Genetic Variants and Protective Immunity against SARS-CoV-2 Genes · 2022 · 5 citations
    9. Evaluation of SARS-CoV-2 Entry, Inflammation and New Therapeutics in Human Lung Tissue Cells bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 3 citations
    10. Evaluation of SARS-CoV-2 entry, inflammation and new therapeutics in human lung tissue cells PLoS Pathogens · 2022 · 1 citations
    11. Antiviral effects of human placenta hydrolysate (Laennec®) against SARS-CoV-2 in vitro and in the ferret model The Journal of Microbiology · 2021 · 13 citations
    12. Rat steroid 5α-reductase kinetic characteristics: Extreme pH-dependency of the type II isozyme in prostate and epididymis homogenates The Journal of Steroid Biochemistry and Molecular Biology · 1995 · 13 citations
    13. Type 1 interferon signature and cytotoxic T lymphocyte activation targeted against sweat ducts in inflammatory acquired idiopathic generalized anhidrosis Journal of the European Academy of Dermatology and Venereology · 2023 · 6 citations
    14. TYK2 Inhibition with Deucravacitinib Improves Clinical Outcomes and Resolves Interferon-Driven Inflammation in Lichen Planopilaris 2026
    15. Understanding the Role of Type I Interferons in Cutaneous Lupus and Dermatomyositis: Toward Better Therapeutics Arthritis & Rheumatology · 2024 · 14 citations
    16. K6irs1, K6irs2, K6irs3, and K6irs4 Represent the Inner-Root-Sheath-Specific Type II Epithelial Keratins of the Human Hair Follicle1 Journal of Investigative Dermatology · 2003 · 130 citations
    17. Type II Epithelial Keratin 6hf (K6hf) Is Expressed in the Companion Layer, Matrix, and Medulla in Anagen-Stage Hair Follicles Journal of Investigative Dermatology · 2003 · 60 citations
    18. Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells Molecular Biology of the Cell · 2002 · 80 citations
    19. A Novel Type II Cytokeratin, mK6irs, is Expressed in the Huxley and Henle Layers of the Mouse Inner Root Sheath Journal of Investigative Dermatology · 2001 · 45 citations
    20. The influence of interferon on healthy and diseased skin Cytokine · 2018 · 32 citations
    21. A homozygous missense variant in type I keratin <i>KRT25</i> causes autosomal recessive woolly hair Journal of Medical Genetics · 2015 · 29 citations
    22. Plasmacytoid dendritic cells in alopecia areata: missing link? Journal of the European Academy of Dermatology and Venereology · 2014 · 45 citations
    23. Cutaneous Drug Eruptions Associated with the Use of Biologies and Cutaneous Drug Eruptions Mimicking Specific Skin Diseases Chemical Immunology · 2012 · 4 citations
    24. Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia (Alopecia Areata) in a C3H/HeJ Mouse Model ˜The œAmerican journal of pathology · 2008 · 69 citations
    25. PD23-01 INHIBITOR OF 5A-REDUCTASE TYPES II PROMOTES THE INFILTRATION OF CD8+T CELLS IN BPH TISSUES. The Journal of Urology · 2014
    26. What’s Sex Got to Do With COVID-19? Gender-Based Differences in the Host Immune Response to Coronaviruses Frontiers in Immunology · 2020 · 125 citations
    27. Potential Role of Cinnamon (<i>Cinnamomum verum</i>) to Reduce the Risk of Polycystic Ovary Syndrome by Managing the Obesity: A Review Journal of food and nutrition research · 2022 · 1 citations
    28. Significance of stress keratin expression in normal and diseased epithelia iScience · 2024 · 47 citations
    29. Advances in molecular pathogenesis of hidradenitis suppurativa: Dysregulated keratins and ECM signaling Seminars in cell & developmental biology · 2022 · 5 citations
    30. Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model Frontiers in Immunology · 2020 · 48 citations