July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study developed a 3D ovarian cancer model using microtumours, which effectively mimics minimal residual disease and supports the identification of new drug targets like perhexiline for treatment-resistant cells.
82 citations
,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
January 2024 in “Dermatologic Therapy” This retrospective study found that oral tofacitinib significantly reduced the severity of alopecia areata in children, achieving over a 50% reduction in hair loss severity, though relapse occurred during treatment tapering, and mild adverse effects were noted.
January 2013 in “Tampere University Institutional Repository (Tampere University)” This study observed that Tudor-SN protein may play a significant role in the immune system and that polyamines can influence hair growth in a mouse model.
1 citations
,
March 2004 in “Journal of the American Academy of Dermatology” This study discusses two cases of acneiform skin eruptions associated with the use of the EGFR inhibitor ZD1839 in prostate cancer treatment, emphasizing the need for dermatologists to be aware of potential skin reactions.
1 citations
,
January 2023 in “International Journal of Molecular Sciences” This review explores the role of Tregs in autoimmune skin diseases, transplantation, and skin cancer, and discusses Tregs-based therapies' potential for treating autoimmunity without reporting new experimental results.
11 citations
,
January 2020 in “Dermatologica Sinica” This study found that tofacitinib effectively promoted hair regrowth in Asian patients with severe alopecia areata, with 74.3% showing a clinical response.
August 2025 in “Journal of the American Academy of Dermatology” 1 citations
,
October 2015 in “Interest : Jurnal Ilmu Kesehatan” In this study, both gel and microemulsion formulas containing waru leaves and Java Tamarind extracts were found to have similar in vivo hair growth activity in rabbits.
November 2022 in “Journal of the Endocrine Society” This case study highlighted that excessive iodide intake from the supplement TauriNac was associated with the development of hypothyroidism in a cystic fibrosis patient, which reversed upon discontinuation.
34 citations
,
January 2023 in “Therapeutic Advances in Medical Oncology” This study found that the safety and effectiveness of sacituzumab govitecan in patients with metastatic triple-negative breast cancer in Germany align with existing clinical trial data.
9 citations
,
May 2021 in “International Journal of Dermatology” In this study, sublingual tofacitinib achieved a longer estimated half-life than oral administration in treatment-resistant alopecia areata patients, potentially supporting daily dosing; overall treatment response was modest.
22 citations
,
March 2017 in “Journal of the Formosan Medical Association” This report presents the Taiwanese Dermatological Association's 2016 consensus on defining and managing skin toxicities from EGFR-TKI treatments, providing comprehensive guidelines for clinicians in Taiwan.
June 2026 in “Khyber Journal Of Medical Sciences” This study found that among adults with severe alopecia areata, alopecia totalis, or alopecia universalis, oral tofacitinib was more effective than methotrexate in reducing hair loss over a 12-week period, though long-term safety and efficacy remain unestablished.
February 2026 in “ACS Omega” This study developed a multifunctional hydrogel, QTMP-Gel, which significantly accelerated wound healing in an oral mucositis hamster model by providing antioxidant and antibacterial effects, reducing inflammation, and controlling infection.
26 citations
,
June 2022 in “Stem Cell Research & Therapy” This study found that Tideglusib enhances wound healing in aged rats by activating the PI3K/Akt pathway, suggesting its potential for medical and cosmetic applications targeting age-related skin changes.
9 citations
,
March 2022 in “Frontiers in Immunology” This review discusses the roles and mechanisms of tissue-resident regulatory T cells in immune regulation and tissue homeostasis, but reports no new experimental results.
26 citations
,
April 2019 in “Advances in wound care” This study found that tannic acid accelerated wound healing in rats by modulating inflammatory cytokines, increasing growth factors, and activating the Erk 1/2 pathway.
3 citations
,
June 2001 in “Journal of Zoo and Wildlife Medicine” This case study reported that after removal of an interstitial cell tumor from a ruffed lemur, the animal experienced improved coat quality and a return to normal behavior without signs of cancer spread.
8 citations
,
January 2014 in “Annals of Dermatology” This study found that TGF-β1 expression in follicular tumors correlates with differentiation degree and suggests its potential role alongside p63 in differentiating between sebaceous and follicular tumors.
245 citations
,
January 2018 in “Bone Research” This review discusses the role of TGF-β signaling in stem cell recruitment and tissue regeneration, indicating that abnormalities in TGF-β activation contribute to various major diseases and suggesting avenues for therapeutic intervention.
238 citations
,
November 2016 in “Journal of The American Academy of Dermatology” In this study, tofacitinib was reported to improve scalp hair regrowth in patients with severe alopecia areata, alopecia totalis, and alopecia universalis, showing a higher response in alopecia areata.
3 citations
,
August 2018 in “Journal der Deutschen Dermatologischen Gesellschaft” The technique effectively repairs skin after tumor removal, maintaining appearance and function without complications.
8 citations
,
November 2013 in “PLOS ONE” In this study, researchers found that a subset of mammary cells with active Wnt signaling in mice does not develop tumors upon ErbB2 activation and instead undergoes apoptosis, potentially protecting against carcinogenesis.
April 2023 in “Journal of Investigative Dermatology” This study found that an automated tumor-infiltrating lymphocyte classification algorithm identified thin melanomas with less immune response, which were associated with higher mortality compared to other cases in the study.
3 citations
,
September 1973 in “Archives of dermatology” This study reports that daily topical application of a 0.05% tretinoin solution can eliminate the hair plugs and symptoms associated with trichostasis spinulosa.
5 citations
,
June 2016 in “University of Zagreb University Computing Centre (SRCE)” This study observed that canine follicular tumors are an uncommon type of skin neoplasia in Croatian dogs, often benign but with a small percentage presenting malignancy, and vary based on the breed's hair growth type.
January 2017 in “International journal of science and research” This review discusses treatment options for trichotillomania, focusing on cognitive-behavioral interventions and promising developments in combined pharmacotherapy and therapy approaches, but reports no new findings.
4 citations
,
April 2015 in “대한비뇨기종양학회지” This study concluded that packaging tamsulosin and finasteride together for co-administration in patients with benign prostatic hyperplasia improves medication adherence compared to packaging each drug separately.
40 citations
,
September 2018 in “Journal of the American Academy of Dermatology” This letter discusses the emerging use of Janus kinase inhibitors, specifically oral tofacitinib, for treating alopecia areata in children, but reports no new clinical findings.