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The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

People with hair loss conditions experience more anxiety, depression, and a lower quality of life than those without these conditions.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Fractional laser resurfacing is effective and safe for skin treatment, with benefits like less downtime and a low risk of adverse events.

Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.

Skin cell clumping for hair growth is improved by a protein called fibronectin, which helps cells stick and move better.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

CLE40 and CRN/CLV2 pathways have opposite effects on root growth in Arabidopsis.

Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.

Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.

The review suggests that understanding and treating the psychological aspect of skin disorders is important and calls for more collaboration in this field.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.

Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.

Vitamin D3 analogs can promote hair growth in mice genetically prone to hair loss.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Epidermal keratinocytes start wound healing and inflammation after schistosome infection.

Three new types of a skin blistering disease were found, caused by specific gene mutations.

Finasteride may help reduce symptoms in male Tourette syndrome patients.

Skin diseases are very common in poor areas, and there's a need for affordable ways to manage and improve skin health.

Using steroids can increase the risk of heart problems.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Many skin patients have mental health issues, but few dermatologists are well-versed in treating these conditions.

The nutritional supplement improved hair density and reduced hair loss in women with female pattern hair loss.

The document suggests medicine should integrate biological and cultural factors and focus on holistic, equitable care.

The debate on direct-to-consumer pharmaceutical ads continues, with consumers finding them educational and doctors concerned about their impact on patient relationships and medication understanding.

High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.

Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.