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Humans lost body hair relatively recently in evolution.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Stem cell self-renewal is complex and needs more research for full understanding.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Understanding hair follicle anatomy helps diagnose hair disorders.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Hair loss can significantly affect a person's self-esteem and body image, especially in young people, those who value their looks highly, and women.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Horizontally sectioned scalp biopsies are more reliable for diagnosing hair loss in women when three samples are taken instead of one.

Minoxidil increases blood flow in balding scalps, possibly reversing hair loss.

Finasteride effectively blocks enzyme causing male pattern baldness.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Forehead modification greatly increases the perception of femininity and is a safe procedure.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Tempol is safe and may prevent hair loss from brain radiotherapy.