2 citations
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January 1966 in “American Journal of Obstetrics and Gynecology” This study observed that thyroid and hormone treatments did not resolve postpartum alopecia in a small patient group, and most cases may naturally revert to normal.
5 citations
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May 2007 in “Pediatric Dermatology” This case report of a 15-year-old girl suggests a direct association between extremely severe hypothyroidism and unusual cutaneous manifestations, such as psoriasiform lesions and abscesses, which improved with thyroid supplementation.
12 citations
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July 1957 in “Journal of Investigative Dermatology” This historical observation found that parathyroid extract treatment in newborn rats led to a condition resembling scleroderma, characterized by skin hardening, calcium deposition, and possible necrosis.
11 citations
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January 1989 This case report describes two patients with trichothiodystrophy who exhibited a different pattern of hair protein composition changes, suggesting a subgroup of TTD characterized by partial loss of high-sulfur proteins without significant alteration in their amino acid composition.
The authors concluded that capecitabine and high-dose toremifene may be an effective treatment option for patients unable to undergo anthracycline or taxane therapies, based on one woman's cancer management.
February 2020 in “Central Plains Medical Journal” In this study, combining thalidomide with CHOP treatment showed a significantly higher effective rate in treating peripheral T-cell lymphoma compared to CHOP alone, while both regimens were associated with similar levels of adverse reactions.
5 citations
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January 1964 in “Naunyn-Schmiedeberg s Archives of Pharmacology” Iodine is absorbed by hair just below the skin surface.
11 citations
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December 2010 in “The Journal of Urology” This study found that combining oral testosterone with dutasteride increased testosterone bioavailability in hypogonadal men while suppressing dihydrotestosterone levels over a 28-day period.
83 citations
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July 2004 in “Pharmacology Biochemistry and Behavior” Higher 3α,5α-THP levels in the brain may reduce depression in pregnant rats.
January 2025 in “Biomedical Reports” This case report describes the first successful use of telitacicept in treating a patient with systemic lupus erythematosus and a history of papillary thyroid carcinoma, suggesting its potential as a therapeutic option for such conditions.
3 citations
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August 2023 in “Drug safety” This source reports that trastuzumab deruxtecan improves outcomes in HER2-positive and HER2-low metastatic breast cancer, emphasizing the need for careful adverse event monitoring, particularly for interstitial lung disease, and managing emetic risk to maximize benefits.
75 citations
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January 1980 in “Journal of Investigative Dermatology” 7 citations
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November 1997 in “Pediatric Dermatology” This case report identifies an association between trichothiodystrophy and a urologic malformation with primary hypercalciuria, adding to the spectrum of TTD-related abnormalities.
March 2025 in “World Journal of Meta-Analysis” This integrative review analyzed nutritional interventions for Hashimoto’s thyroiditis (HT) and found that treatments such as micronutrient supplementation, anti-inflammatory diets, and lifestyle changes may help manage symptoms, though the effectiveness varied among studies.
4 citations
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December 2025 in “Frontiers in Immunology” This systematic review of Mendelian randomization studies reports that autoimmune thyroid disease is associated with increased risk for numerous health conditions, including coronary atherosclerosis and rheumatoid arthritis, while decreasing risks for others, such as lung cancer.
January 2026 in “Nutrients” This study observed that while low vitamin D levels are associated with increased risk of autoimmune thyroid diseases, evidence from clinical trials on vitamin D supplementation shows inconsistent effects on thyroid function and disease progression, underscoring the need for further research.
January 2023 in “Voennaâ medicina” This case study illustrates the successful treatment of chronic diffuse telogen effluvium in a young woman attributed to latent iron deficiency and emphasizes the importance of comprehensive assessment in similar cases.
3 citations
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May 2012 in “BMC Endocrine Disorders” This article presents a unique case of post-partum panhypopituitarism and autoimmune conditions in a 37-year-old woman from Africa, emphasizing the need for early diagnosis and treatment to improve outcomes in similar settings.
May 2025 in “Pakistan Armed Forces Medical Journal” This study found that topical Dithranol 0.5% is more effective than topical Tacrolimus 0.1% for hair regrowth in patients with alopecia areata, with 40% of Dithranol-treated patients showing over 80% hair regrowth compared to 23.33% for Tacrolimus-treated patients.
March 2015 in “CRC Press eBooks” This article discusses telogen effluvium in women, its causes, and typical diagnostic methods, but reports no new research findings on clinical outcomes or treatments.
May 2026 in “Sudovo-medična ekspertiza” This study documented three cases of acute thallium poisoning—one involving accidental overdose and two linked to intentional homicide—characterized by neurological and systemic symptoms, and in severe instances, death, underscoring thallium compounds' significant toxicity.
November 2025 in “Journal of Investigative Dermatology” Dithranol reduces inflammation in alopecia areata by lowering certain immune responses.
26 citations
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January 1983 in “PubMed” This study reports that despite normal cystine incorporation into hair follicles, trichothiodystrophy patients have decreased cystine levels in hair shafts, contradicting the hypothesis of defective transport in hair follicles.
29 citations
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October 2020 in “Environmental health perspectives” This study found that several preservatives, including triclocarban and triclosan, showed potential endocrine-disrupting effects on various nuclear receptors in both in silico and in vitro models.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this randomized control trial, the researchers found that intralesional triamcinolone acetonide led to higher hair density increases than Vitamin D supplementation in alopecia areata patients, although potential hair regrowth was also noted with Vitamin D in those with deficient levels.
22 citations
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January 2017 in “Acta Endocrinologica” A woman with multiple autoimmune diseases showed improvement in hair loss but not in skin discoloration after treatment.
12 citations
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January 1987 in “Carcinogenesis” This study found that a single application of TCDD on the skin of hairless mice altered epidermal differentiation, changing keratin expression patterns similarly to a known tumor promoter.
January 2026 in “Endocrinology” 53 citations
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July 2014 in “American Journal of Physiology-Endocrinology and Metabolism” This study found that testosterone-enanthate increased red blood cell production and altered iron homeostasis in older hypogonadal men without being affected by finasteride, indicating these effects do not require type II 5α-reductase enzyme activity.
508 citations
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June 2009 in “Current drug metabolism” This review details the skin and hematological toxicities of tyrosine kinase inhibitors like erlotinib, gefitinib, and imatinib, and highlights ongoing concerns about cardiac toxicity, reporting no new clinical findings.