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    Glossary transcriptional profile

    snapshot of all active genes being transcribed into RNA

    A transcriptional profile is a snapshot of all the genes that are being actively transcribed into RNA in a cell or tissue at a given time. This profile helps scientists understand which genes are turned on or off under specific conditions, providing insights into cellular functions, disease mechanisms, and responses to treatments.

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    Research 30 of 1000+

    1. Coregulation of Genetic Programs by the Transcription Factors NFIB and STAT5 Molecular Endocrinology · 2014 · 20 citations
    2. T Cells Promote Distinct Transcriptional Programs of Cutaneous Inflammatory Disease in Keratinocytes and Dermal Fibroblasts Journal of Investigative Dermatology · 2025 · 2 citations
    3. Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo eLife · 2023 · 23 citations
    4. Synthetically programmed antioxidant delivery by a domesticated skin commensal Cell Systems · 2025 · 8 citations
    5. Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing Cell stem cell · 2020 · 128 citations
    6. RNA Coding and Transcriptional Regulation in Skin Repair: Insights from Single-Cell Profiling and Implications for Organoid-Based Regenerative Strategies Life · 2026
    7. Deciphering gene regulatory programs in mouse embryonic skin through single-cell multiomics analysis Genome biology · 2025
    8. A molecular wound response program associated with regeneration initiation in planarians Genes & Development · 2012 · 212 citations
    9. Micro‐RNA‐31 controls hair cycle‐associated changes in gene expression programs of the skin and hair follicle ˜The œFASEB journal · 2010 · 149 citations
    10. 0975 Single-cell transcriptomic profiling reveals distinct immunopathogenic programs in alopecia totalis/universalis compared to patchy alopecia areata Journal of Investigative Dermatology · 2026
    11. Cellular plasticity in reprogramming, rejuvenation and tumorigenesis: a pioneer TF perspective Trends in Cell Biology · 2023 · 45 citations
    12. Human melanocyte development and melanoma dedifferentiation at single cell resolution bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 9 citations
    13. Polycomb repressive complex 2 in adult hair follicle stem cells is dispensable for hair regeneration PLoS Genetics · 2021 · 6 citations
    14. Characterizing the cellular diversity and molecular signatures within the hair follicle dermal stem cell lineage PRISM (University of Calgary) · 2017
    15. Mediator 1 ablation induces enamel-to-hair lineage conversion through enhancer dynamics bioRxiv (Cold Spring Harbor Laboratory) · 2022
    16. Author response: Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria 2014 · 3 citations
    17. Decision letter: Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria 2014
    18. POLYCOMB REPRESSIVE COMPLEX 1 IS REQUIRED TO MAINTAIN STEM CELL IDENTITY AND TO PRESERVE ADULT TISSUE HOMEOSTASIS. Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) · 2020
    19. High-resolution single cell transcriptome analysis of zebrafish sensory hair cell regeneration bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 3 citations
    20. Distinct tooth regeneration systems deploy a conserved battery of genes bioRxiv (Cold Spring Harbor Laboratory) · 2020
    21. In Silico Analysis of the Age-Dependent Evolution of the Transcriptome of Mouse Skin Stem Cells Cells · 2020 · 4 citations
    22. Deletion of an Enhancer in FGF5 is Associated With Ectopic Expression in Goat Hair Follicles and the Cashmere Growth Phenotype Research Square (Research Square) · 2020 · 1 citations
    23. Deletion of an enhancer in FGF5 is associated with ectopic expression in goat hair follicles and the cashmere growth phenotype Research Square (Research Square) · 2020
    24. 869 The specification of Merkel cell in the back skin and glabrous paw skin is controlled by FGFR2-meditated signaling Journal of Investigative Dermatology · 2019
    25. A stretch-responsive fibroblast program promotes epidermal stem cell self-renewal during skin expansion Nature Communications · 2026
    26. A transient dermal niche and dual epidermal programs underlie sweat gland development bioRxiv (Cold Spring Harbor Laboratory) · 2023
    27. 0140 Delineating key molecular programs that induce hair-follicle-inductive dermal fibroblasts using a novel single-cell genomic approach Journal of Investigative Dermatology · 2025
    28. FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program Frontiers in Immunology · 2013 · 69 citations
    29. Mediator 1 ablation induces enamel-to-hair lineage conversion in mice through enhancer dynamics Communications biology · 2023 · 1 citations
    30. Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle The EMBO Journal · 2000 · 305 citations