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PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.

Hair growth is cyclic and influenced mainly by local factors.

Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Fat-related cells are important for initiating hair growth.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

A mother's diet at conception can cause lasting genetic changes in her child.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

Targeting colon cancer stem cells might lead to better treatment results.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.