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Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

New cancer treatments are more precise and less toxic, improving survival rates, but Asia faces challenges in adopting these advancements.

Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.

The document advises health care providers on how to support transgender and gender-diverse youth with appropriate care and referrals.

Gender identity can be more diverse than just male or female.

Possible link between hair loss and metabolic syndrome, with RANTES as a potential clue.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Treating PCOS is complex, involving medication like metformin and lifestyle changes, and requires attention to mental health due to high depression and anxiety rates.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

CBD may improve skin and hair health, but its effective use and safety need more research.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Autologous cellular micrografts improve hair density and thickness in the short term for androgenetic alopecia.

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Use telemedicine and strict hygiene for safe hair and scalp treatments during COVID-19.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Oestrogens are key for bone growth during puberty in both boys and girls.

Pantethine may boost the immune system's ability to fight sarcoma.