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research 1419 Pre-clinical in-vitro assays for high throughput screening of drug candidates for protection and restoration of immune privilege in alopecia areata
This research developed new in vitro models for high-throughput screening of drugs that could protect or restore immune privilege in hair follicles, finding that Tofacitinib was effective in preventing inflammation-related marker upregulation, while Tacrolimus and αMSH worked specifically in outer root sheath keratinocytes.
research Adult-onset porokeratotic eccrine ostial and dermal duct nevus:dermatoscopic findings and treatment with tazarotene
In this case report, adult-onset porokeratotic eccrine ostial and dermal duct nevus improved with topical tazarotene treatment, as evidenced by dermatoscopic images.
research Effect of thioredoxin reductase 1 on glucocorticoid receptor activity in human outer root sheath cells
This study suggests that decreased expression of thioredoxin reductase 1 in hair follicle cells may contribute to glucocorticoid resistance in some alopecia areata patients by affecting the intracellular redox system.
research 62823 Optimization of deuruxolitinib dosing in adult patients with alopecia areata: Results from a randomized, parallel-group, multicenter, Phase 2 trial
The trial helped find the best dose of deuruxolitinib for treating alopecia areata.
research Effectiveness of QR678 and QR678 Neo ® with intralesional corticosteroid vs. intralesional corticosteroid alone in the treatment of alopecia areata –A randomized, comparative, prospective study
The researchers reported that QR678 Neo® combined with intralesional steroids significantly improved hair regrowth and patient satisfaction in treating alopecia areata compared to steroids alone.
research 매선 치료 및 약침 치료로 개선된 여성형 탈모 환자 1례
This study found that pharmacopuncture and needle-embedding therapy may improve hair loss and physical condition in women with androgenetic alopecia, though further clinical research is needed.
research Therapeutic indications and other use-case-driven updates in the drug ontology: anti-malarials, anti-hypertensives, opioid analgesics, and a large term request
This study expands the Drug Ontology to include therapeutic indications for resistant hypertension, malaria, and opioid abuse research, providing a framework for additional drug use representations beyond their original design.
research Successful Treatment of Temporal Triangular Alopecia with Topical Minoxidil
Topical minoxidil successfully treated temporal triangular alopecia.
research Treatment of intralesional corticoisteroid-induced cutaneous atrophy with hyaluronic acid filling
This case report describes a treatment approach for frontal and temporal alopecia using oral dutasteride, minoxidil lotion, and triamcinolone injections, with hyaluronic acid successfully treating injection site atrophy.
research Follow-up
research Intermittent Use of Testosterone Inactivating Pharmaceuticals Using Finasteride Prolongs the Time Off Period
Using finasteride with TIP extends time off period for prostate cancer patients.
research Standardizing the Classification and Description of Follicular Unit Transplantation and Mini-Micrografting Techniques
This article proposes a classification for small graft transplants that includes technical factors to improve communication and facilitate comparative studies, reporting no new clinical results.
research Safety and efficacy of actinic keratoses reduction with a 3 day application of ingenol disoxate field treatment to the face, chest and balding scalp
This phase 2 trial found that SM04554, a Wnt signaling modulator, was well-tolerated and increased follicle counts in males with androgenetic alopecia, suggesting potential for promoting hair growth.
research Loose anchoring of anagen hairs and pili torti due to erlotinib
This case report describes two patients who experienced loose anagen hairs and pili torti, resulting in nonscarring alopecia, potentially linked to erlotinib treatment for solid tumors.
research [Dose/effect correlation in topical minoxidil therapy of androgenic alopecia].
More minoxidil applied topically leads to better hair growth in male pattern baldness.
research An Idea Whose Time Has Come
This article discusses the author's experience attending the annual Italian Society for Hair Restoration meeting and does not report any scientific findings.
research Finasteride plus doxazosin combination tops in BPH
research Patient Selection, Hair Transplant Design, and Hairstyle
This article discusses patient selection and procedural design for hair transplant surgery without reporting new clinical results; it also considers how hair transplant designs can align with various hairstyles.
research Efficient delivery of transgenes to human hair follicle progenitor cells using topical lipoplex
research COMPARATIVE EVALUATION OF EFFICACY AND SAFETY OF TOPICAL METHOTREXATE WITH TRETINOIN VERSUS BETAMETHASONE WITH TRETINOIN IN PATIENTS OF ALOPECIA AREATA: A PROSPECTIVE RANDOMIZED DOUBLE-BLIND STUDY
This study at Gajra Raja Medical College found that topical methotrexate with tretinoin was more effective but not significantly better than betamethasone with tretinoin for treating alopecia areata over six months, with similar safety profiles between the treatments.
research Olmsted Syndrome Caused by a Homozygous Recessive Mutation in TRPV3
Olmsted syndrome can be inherited as an autosomal recessive trait due to a rare TRPV3 gene mutation.
research The Retinoic-Acid-Related Orphan Receptor Alpha May Be Highly Involved in the Regulation of Seasonal Hair Molting
This study found that melatonin may enhance hair follicle stem cell viability by downregulating the nuclear receptor RORA, which otherwise inhibits cell proliferation and promotes apoptosis.
research Hair Transplantation surgery
This article reviews the principles of donor and recipient dominance in hair transplantation and reports no new experimental results.
research Twice weekly 5 mg betamethasone oral pulse therapy in the treatment of alopecia areata
This article reports on twice-weekly 5 mg betamethasone oral pulse therapy for alopecia areata but provides no clinical results.
research Occipital Hair Loss in a 26-Year-Old Man
The man's occipital hair loss was due to temporal triangular alopecia, not alopecia areata.
research Correction: Oral Minoxidil Therapy in Hair Loss: Where Do We Stand?
Oral minoxidil is a potential treatment for hair loss.
research A Survey of Patient Attitudes Towards Topical Minoxidil in the Treatment of Hair Loss.
This abstract describes androgenetic alopecia, a common dermatological condition, and does not provide new clinical findings.
research PA31 Traction alopecia in the paediatric Sikh population
In this study, researchers described cases of traction alopecia in young Sikh boys due to hair tying practices, emphasizing the importance of early intervention and education to prevent progression and support hair regrowth, using strategies like changing hair tying methods and topical treatments when appropriate.
research 153 Effectiveness of OR-101, a next generation highly selective JAK3 inhibitor, in a humanized murine model of alopecia areata
This study found that OR-101, a selective JAK3/TEK inhibitor, was associated with dose-dependent improvements in hair growth in humanized mice with alopecia areata, suggesting its potential as a treatment option.