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Lipid Nanoparticles for Topical and Transdermal Application for Alopecia Treatment: Development, Physicochemical Characterization, and In Vitro Release and Penetration Studies

research Lipid Nanoparticles for Topical and Transdermal Application for Alopecia Treatment: Development, Physicochemical Characterization, and In Vitro Release and Penetration Studies

28 citations, March 2014 in “International Journal of Nanomedicine”

New lipid nanoparticles show promise for delivering hair loss treatments but need improvement for better skin penetration.

research Physical Methods for Topical Skin Drug Delivery: Concepts and Applications

22 citations, November 2018 in “Brazilian Journal of Pharmaceutical Sciences”

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% Versus Minoxidil 5% Solution in Male Androgenetic Alopecia

research An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% Versus Minoxidil 5% Solution in Male Androgenetic Alopecia

21 citations, January 2017 in “Skin Pharmacology and Physiology”

Caffeine-based liquid 0.2% is as effective as minoxidil 5% for treating male hair loss.

Platelet-Rich Plasma in Combination With 5% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study

research Platelet-Rich Plasma in Combination With 5% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study

19 citations, May 2017 in “Dermatologic Surgery”

Combining platelet-rich plasma with 5% minoxidil solution improves hair regrowth in androgenetic alopecia patients.

research Pigmented Contact Dermatitis from Topical Minoxidil 5%

17 citations, April 2002 in “Contact Dermatitis”

Minoxidil 5% caused skin discoloration in a man using it for hair loss.

research Severe Dermographism After Topical Therapy With Diphenylcyclopropenone for Alopecia Universalis

16 citations, April 2000 in “Contact dermatitis”

A man developed severe skin reactions after using a treatment for hair loss.

research Effect of Topical Linum Usitatissimum on Full Thickness Excisional Skin Wounds

15 citations, September 2016 in “Trauma Monthly”

Linum usitatissimum gel improves wound healing and tissue regeneration.

research Contact Dermatitis Due to Topical Traditional Chinese Medication

15 citations, July 1997 in “Clinics in Dermatology”

Traditional Chinese medications can cause skin reactions, and better testing and reporting are needed to identify allergens.

research A Systematic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Prevent Androgenic Alopecia

14 citations, October 2020 in “Natural Products and Bioprospecting”

Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.

research Effects of Topical Application of EGCG on Testosterone-Induced Hair Loss in a Mouse Model

14 citations, July 2011 in “Experimental Dermatology”

Applying EGCG on the skin can prevent hair loss caused by testosterone in mice.

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