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The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

Menopause affects hair and skin; more research needed for treatment.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

People with myotonic dystrophy type 1 have a higher chance of getting skin tumors, including melanoma.

Recognizing and treating skin symptoms in essential thrombocythemia is crucial for patient quality of life.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Breast implants are linked to autoimmune symptoms, with over half of patients feeling better after removal, but the exact cause is unclear and may involve bacterial biofilm.

Overexpressing SIMK in alfalfa boosts root hair growth, nodule clustering, and shoot biomass.

New genes linked to ichthyosis were found, but there's still no cure; treatment options are improving.

Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Removing anthrax toxin receptor 1 in pigs prevents Senecavirus A infection and causes a rare disease similar to GAPO syndrome.

The document concludes that periocular hair disorders have various causes and treatments, and proper evaluation by specialists is important for management and prognosis.

Older patients with Cushing's syndrome often have different symptoms and treatment outcomes compared to younger patients.

The skin has about 230,000 touch-sensitive nerve fibers, with high concentrations in the hands and face.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

Scalp basal cell carcinoma may be more aggressive and harder to treat than other types, requiring special attention and further research.

Tacrolimus is an effective treatment for several skin conditions with fewer side effects than cyclosporine.

Traditional Chinese Medicine and acupuncture may improve Polycystic Ovarian Syndrome symptoms and reduce costs, but more research is needed.

Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.

Iron nanoparticles made from pumpkin extract effectively treated burns and promoted healing in mice.

People with polycystic ovary syndrome are more likely to have poor sleep, restless legs syndrome, anxiety, and depression.

MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.