research Cerebellar Medulloblastoma: Treatment by Irradiation of the Whole Central Nervous System
Irradiating the whole central nervous system can lead to over 50% of patients with cerebellar medulloblastoma surviving three years.
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research Adrenocortical Adenoma as a Cause of Hyperandrogenism Syndrome in a Girl: The Path to Diagnosis
A young girl's hyperandrogenism was caused by an adrenocortical adenoma, diagnosed and treated through detailed evaluations.
research Baricitinib Demonstrates Rapid Action Within Just 2 Months of Treatment in Severe and Unresponsive Alopecia Areata: A Case Report
Baricitinib quickly improved severe alopecia areata, with almost total hair regrowth in three months.
research Phase-Specific Differential Regulation of Mechanical Allodynia in a Murine Model of Neuropathic Pain by Progesterone
Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.
research Advances in Mitochondria-Centered Mechanism Behind the Roles of Androgens and Androgen Receptor in the Regulation of Glucose and Lipid Metabolism
Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
research Follicular Dysplasia and Hair Loss in White-Tailed Deer (Odocoileus Virginianus)
White-tailed deer can get a hair loss condition that might make them more vulnerable to environmental threats.
research Mucocutaneous Presentations of Critical and Non-Critical Admitted COVID-19 Patients and Vaccine-Associated Dermatoses: A Study from Iran
The study found that skin conditions in COVID-19 patients can signal serious internal organ damage and may be life-threatening.
research Surfactants' Role in Nanovesicles Drug Delivery System
Surfactants in spanlastics improve drug delivery by making nanovesicles more flexible and stable for painless administration through the mouth.
research Alopecia Areata: Diagnostic and Therapeutic Recommendations of the Polish Dermatological Society, Part 1: Diagnosis and Severity Assessment
There are two main types of alopecia areata with different severity, and diagnosis is made through clinical examination and trichoscopy, influencing treatment choices.
research Depth Control in Follicular Unit Excision: A New Classification from a Detailed Analysis of 30 Patients Undergoing FUE Technique for Hair Restoration
A new classification for depth control in hair restoration surgery was proposed, dividing it into three grades based on the depth required for successful graft extraction.
research Polymer Conjugated Retinoids for Controlled Transdermal Delivery
A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with less inflammation.
research Inducing Hair Follicle Organogenesis With Defined Environmental Protein Factors
Protein extract from embryonic skin can create new hair follicles in adult life, primarily through effects on fibroblasts.
research 5-Bromo-2′-Deoxyuridine Induced Effluvium via p53-Mediated CD326-Positive Keratinocyte Apoptosis in C57BL/6 Mice
A chemical called 5-Bromo-2′-deoxyuridine caused rapid hair loss in mice by killing certain skin cells through a specific cell death pathway.
research Topical Application of Anti-Cancer Drug Bortezomib Stimulates Proliferation of Follicular Cells and Induces Expression of Hair Keratins via GATA-3 Transcription Factor
Applying the anti-cancer drug Bortezomib to skin can promote hair growth and increase hair proteins through the GATA-3 factor.
research Electronic Brachytherapy for the Treatment of Nonmelanoma Skin Cancer: Results at 3 Years
High dose rate electronic brachytherapy is an effective and safe non-surgical treatment for nonmelanoma skin cancer with good cosmetic results after three years.
research Restoring Dry, Damaged Hair with a Novel Natural Wheat Protein and Wheat Germ Oil-Containing Shampoo and Conditioner Line
The shampoo and conditioner improved dry, damaged hair significantly after three uses.
research Management of Pregnancy in a Carrier of the Donohue Mutation
Pregnancies in a woman with the Donohue mutation were managed with genetic testing, resulting in three healthy infants.
research Minoxidil, Platelet-Rich Plasma (PRP), or Combined Minoxidil and PRP for Androgenetic Alopecia in Men: A Cost-Effectiveness Markov Decision Analysis of Prospective Studies
Minoxidil alone is the most cost-effective treatment for male hair loss at a $50,000 threshold.
research Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan
Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.
research An Update on Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.
research Size-Dependent Penetration of Nanoemulsions into Epidermis and Hair Follicles: Implications for Transdermal Delivery and Immunization
Smaller nanoemulsions can penetrate skin and hair follicles better, which may be useful for delivering drugs and vaccines through the skin.
research Combination of Herbal Extracts and Platelet-Rich Plasma Induced Dermal Papilla Cell Proliferation: Involvement of ERK and Akt Pathways
Herbal extracts and platelet-rich plasma together may help increase hair growth by making certain cells grow more, through specific cell growth pathways.
research The Efficacy of Platelet-Rich Plasma in Hair Restoration and Facial Aesthetics: A Systematic Review and Meta-Analysis
Platelet-Rich Plasma (PRP) therapy can promote hair growth and improve facial aesthetics, including reducing acne scars and facial burns, and it works best with three initial monthly injections.
research Current Evaluation of Amenorrhea
Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.
research Physical Methods for Topical Skin Drug Delivery: Concepts and Applications
New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
research Face Transplantation for Granulomatosis With Polyangiitis (Wegener Granulomatosis)
Face transplant for a severe autoimmune disease patient was successful, improving appearance and function without disease relapse after three years.
research Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor
Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.
research Management of Clinical Side Effects of Depot Medroxyprogesterone Acetate
To improve use of the contraceptive DMPA among adolescents, effectively manage side effects like menstrual changes and weight gain through counseling and guidance.
research Group A Streptococcal Sepsis and Arthritis
A woman got a serious strep infection from an IUD, likely passed from her husband's infected throat during sexual activity.
research Mites and the Mighty: The Last Work and Lasting Legacy of Albert M. Kligman, PhD, MD
Albert M. Kligman made major contributions to dermatology, including inventing a stain for fungi and advancing knowledge on skin diseases, and his legacy continues through his trainees and philanthropy.