Hair thickening procedures can help people with early hair loss when combined with proper scalp and hair care.
6 citations
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January 2017 in “Journal of toxicologic pathology” This study suggests that the patchy thickening and reddish discoloration in rabbit skin during the hair cycle may be due to large anagen-phase hair follicles compressing the dermis and increased blood vessels causing redness.
5 citations
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January 2015 in “Skin appendage disorders” This study found that pigmented hair-thickening fibers improved the appearance of scalp alopecia in patients with epidermolysis bullosa, although they may cause pruritus and should be used cautiously.
2 citations
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May 2024 in “BMC Genomics” This study analyzed the genetics of the patchiness phenotype in New Zealand rabbits and found that the gene KRT82, with identified SNPs in its promoter, may serve as a potential biomarker for breeding these rabbits.
February 2024 in “International Journal of Health and Pharmaceutical” In this study, Avemor, a tonic containing aloe vera and moringa oleifera, along with varying concentrations of dried moringa leaf extracts, was tested on rabbits for hair growth, but the results showed variable effectiveness compared to a minoxidil control.
13 citations
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October 2016 in “Acta Biochimica et Biophysica Sinica” This study found that GhPLDα1 in upland cotton may be involved in fiber development, correlating with increased hydrogen peroxide and cellulose biosynthesis during secondary cell wall thickening.
19 citations
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September 2010 in “Journal of the European Academy of Dermatology and Venereology” This study found that while the CLASI is generally useful for assessing disease activity and damage in cutaneous lupus erythematosus, it may not accurately reflect all subtypes, indicating a need for revision.
3 citations
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January 1985 in “Drug development and industrial pharmacy” In this study, formulations of a typical lotion shampoo with ethanol or propylene glycol increased the in-vitro release rate of zinc pyrithione, an anti-dandruff agent.
January 2024 in “Revista Dermatológica Centro Uraga” This case report describes a 68-year-old woman diagnosed with chronic cutaneous lupus, characterized by irregular plaques with distinct pigmentation and scarring alopecia, confirmed through histopathology revealing specific skin changes.
January 2015 in “Hair transplant forum international” Up to 10% of hair loss patients might have early signs of a condition called Lichen Planopilaris.
338 citations
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April 2001 in “Current Biology” This study found that transient activation of c-Myc in transgenic mice stimulates keratinocyte proliferation and sebocyte differentiation, affecting normal epidermal and hair follicle development.
252 citations
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November 1995 in “The EMBO Journal” Blocking EGFR in mice causes hair loss and skin changes.
201 citations
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May 2001 in “Proceedings of the National Academy of Sciences” This study found that transgenic expression of COX-2 in mouse basal keratinocytes causes epidermal hyperplasia and certain dysplastic features at specific body sites.
152 citations
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April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study presents evidence that keratitis–ichthyosis–deafness syndrome is caused by a mutation in the connexin 26 gene, expanding the gene's known involvement in various disorders.
148 citations
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May 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that mice lacking the vitamin D receptor (VDR) developed skin tumors more rapidly than those with normal VDR activity, regardless of 1,25-dihydroxyvitamin D(3) presence.
135 citations
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December 2006 in “PLoS Medicine” This study suggests that intermediate-size hyaluronate fragments may enhance keratinocyte proliferation and improve skin thickness in atrophic conditions through a CD44-dependent mechanism.
127 citations
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July 2002 in “EMBO journal” This study found that RXRα/RARγ heterodimers are necessary for retinoic acid-induced keratinocyte proliferation in the skin, while normal epidermal maintenance does not require RAR-mediated signaling.
100 citations
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August 2008 in “American Journal Of Pathology” This study found that epidermal VEGF is crucial for maintaining skin barrier function in mice and may help explain psoriasis development following skin trauma due to its effects on angiogenesis and hyperplasia.
96 citations
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January 1997 in “Clinics in Dermatology” This study found that G protein-coupled estrogen receptor enhances melanin synthesis in melanoma cells through cAMP-PKA-MITF-TYR signaling, suggesting its potential as a drug target for chloasma treatment.
82 citations
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March 2013 in “PLoS ONE” In this study, vemurafenib was associated with a wide range of cutaneous side effects in patients with advanced melanoma, including photosensitivity and various skin and hair changes, necessitating regular dermatological management.
81 citations
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February 2014 in “EMBO molecular medicine” This study found that prolonged Nrf2 activation in mouse keratinocytes led to enlarged sebaceous glands, hair loss, and cysts, suggesting a role for Nrf2 in conditions like MADISH.
81 citations
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September 2005 in “The American journal of pathology” This study found that activin affects both stromal cells and keratinocytes in skin morphogenesis and repair, with dose-dependent effects on keratinocytes demonstrated through transgenic mouse models.
78 citations
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April 1994 in “Archives of dermatology” This study suggests genetic and clinical heterogeneity in keratosis pilaris atrophicans, with variations in inheritance patterns, severity, and response to treatment among 21 individuals observed.
58 citations
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January 2020 in “International Journal of Molecular Sciences” This review evaluates various kits for isolating platelet-rich plasma using established processing standards and finds they enable compliance with consensus quality criteria; ongoing research is needed to refine these procedures for improved consistency and safety.
54 citations
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May 2001 in “Journal of Investigative Dermatology” This study suggests that increased putrescine levels may disrupt normal hair follicle development in transgenic mice, leading to hair loss and altered skin structure, yet these mice appear more resistant to skin tumorigenesis.
52 citations
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March 2007 in “Dermatologic Therapy” This article describes the development and validation of a standardized instrument for measuring skin involvement in cutaneous lupus erythematosus, aiming to aid future clinical research and trials.
49 citations
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February 2009 in “Maturitas” This review discusses the use of testosterone therapy for low libido in women, noting mixed evidence on breast cancer risk and a lack of long-term safety data.
47 citations
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June 2013 in “Biology of blood and marrow transplantation” This study presents a new mouse model for investigating chronic graft-versus-host disease, highlighting the role of human thymic tissue in developing multiorgan fibrosis driven by human immune cells.
45 citations
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August 1954 in “Experimental Biology and Medicine” This study found that vitamin A dissolved in alcohol penetrates skin quickly and does not impair hair growth, even in large doses, but it does not retard keratinization unlike when dissolved in fatty acids.
41 citations
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October 2017 in “International Journal of Women's Dermatology” This review provides an overview of the physiologic skin changes during pregnancy but reports no new findings, emphasizing the need for physicians to distinguish between benign and potentially pathological conditions.