Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study reported that deleting the MED1 subunit from the MED complex in keratinocytes resulted in disrupted hair differentiation and cycling, leading to hair loss in mice.

This case report describes the youngest known patient with viral-associated trichodysplasia of immunosuppression, where systemic valganciclovir therapy improved facial papule eruptions following cardiac transplantation.

This study observed that the hair loss in homozygous rhino mice is associated with widening of the hair canal due to hyperkeratosis, leading to insufficient support for hair anchoring.

This study demonstrates that exfoliative cutaneous lupus erythematosus in German short-haired pointers involves a cellular and humoral immune response against the epidermal basement membrane, with poor response to immunosuppressive therapy.

This case study reports on a mother and daughter with ichthyosis follicularis, alopecia, and photophobia, noting consistent keratotic eruptions during the mother's pregnancies that improved postpartum.

This research reports a new autosomal recessive mutation in mice, 'lanceolate hair', causing generalized alopecia and hair shaft abnormalities, which may serve as a model for Netherton's syndrome in humans.

This study found that overexpression of sPLA2-X in mice was associated with alopecia and hair follicle abnormalities, highlighting its potential role in hair follicle homeostasis.

In this study, epidermal Notch activation increased jagged 1 expression, leading to skin changes like thickening and blistering, with these effects inhibited when jagged 1 was absent.

This article discusses the complexities of diagnosing and managing polycystic ovary syndrome, highlighting the challenges related to fertility treatment criteria, insulin resistance, and long-term health implications, but reports no new clinical findings.

This article reviews phenotypic variability linked to WNT10A nonsense mutations and does not present new research findings.

This study reports that flaky skin mice exhibit skin and nail features that closely resemble human psoriasis vulgaris, suggesting they may serve as a natural model for this condition.

This study found that conditional knockout of N-WASP in keratinocytes of mice led to skin barrier defects, increased immune cell infiltration, and hyperproliferation of keratinocytes, indicating its crucial role in skin homeostasis.

This study found that mice with a mutation in the Zdhhc13 gene exhibited increased susceptibility to skin cancer, highlighting a potential protective role of palmitoyl acyltransferase in skin carcinogenesis.

This study reports that generalized discoid lupus erythematosus is a recognized canine variant of cutaneous lupus erythematosus, resembling its human counterpart, with varied treatment responses and common relapses.

This study found that hair regrowth in Pomeranians with hair cycle arrest treated with melatonin was not associated with a change in oestrogen receptor-α staining.

This case report presents a 28-year-old man with scarring alopecia unresponsive to topical treatments, alongside a family history of keratosis pilaris and unique curly scalp hair.

This case report indicates that epidermal dysplasia in two West Highland White Terriers might be caused by a reaction to Malassezia infection or self-trauma, rather than being congenital.

This study found that micro-current electrical stimulation may promote hair growth in human hair follicle-derived papilla cells and a mice model by enhancing cell proliferation, migration, and activating key growth pathways.

This study found that DHHC13 is crucial for hair anchoring and skin barrier function, with its deficiency in Zdhhc13(skc4) mice leading to cyclic alopecia and skin abnormalities due to cornifelin deficiencies.

In this case report, lichen myxedematosus associated with hepatocellular carcinoma showed progressive improvement in skin lesions without further treatment following tumor resection.

In this study, researchers found that miR-3606-3p is significantly downregulated in skin fibrosis and correlates with disease severity, with its ability to inhibit key signaling pathways suggesting potential therapeutic applications for conditions like systemic sclerosis and keloids.

This study found that disrupting Lm332 expression in mice changes keratinocyte genetic expression, alters cell shape, and disrupts epidermal homeostasis, despite some compensatory anchorage by hair follicle basal cells.

This case report details a 21-year-old woman with dermatopathia pigmentosa reticularis, presenting with generalized reticulate hyperpigmentation, diffuse noncicatricial alopecia, onychodystrophy, palmoplantar keratoderma, and poorly developed dermatoglyphics.

This study found that newborn mice given 6-aminonicotinamide developed skin, intestinal, and central nervous system lesions, offering insights into the mechanisms of pellagra.

This study found that Gsdma3 mutations in mice led to thicker skin and longer hair infundibula, possibly by negatively regulating β-catenin expression in the epidermis.

This study found that isolated red light may serve as an alternative for photo-immunotherapy without additional photosensitizers, as it did not reduce keratinocyte differentiation markers or increase photo-oxidative damage, unlike treatment with IL-4 or UVA1/blue light.

This study presents a system for evaluating semantic similarity between sentences by using token-based matching and improved similarity measures beyond WordNet.

This case report presents the first evidence of significant antigen presenting cells around hair follicles in a patient with alopecia due to active systemic lupus erythematosus.

This study found that crossbred lambs fed liquid diets with reconstituted cow's milk initially grew wool without crimp, with crimp resuming two weeks post-weaning.

This article discusses key surgical techniques for optimal graft growth in hair transplantation and presents no new research findings.