Hair feels different when touched and rubs together in various ways.
18 citations
,
March 2015 in “Journal of Dermatological Case Reports” This study identified distinctive trichoscopic features that may aid in diagnosing loose anagen hair syndrome, such as rectangular black granular structures, solitary yellow dots, and a predominance of follicular units with single hairs.
June 2018 in “Chinese Journal of Dermatology” This study reported that connective tissue nevi show distinctive dermoscopic and RCM features, with RCM being particularly helpful for diagnosing lesions of less than one year in duration.
May 2026 in “Applied Spectroscopy” This study used Raman spectroscopy and wide-angle X-ray scattering to observe two main α-helix to β-sheet transitions in hair keratin under varying humidity levels, finding that water impacts when these structural changes occur, involving a disordered state.
58 citations
,
November 1969 in “British Journal of Dermatology” This report describes two patients with ichthyosis linearis circumflexa exhibiting symptoms resembling Netherton's disease, noting multiple hair shaft defects and discussing a possible connection to aminoaciduria.
21 citations
,
July 2010 in “International Journal of Cosmetic Science” This study found that hair luster decreases with age in Japanese females, primarily due to an irregular increase in fiber curvature which affects hair alignment.
13 citations
,
April 2023 in “Biochemical Society Transactions” This mini-review highlights emerging themes on how tissue stiffness, a fundamental material property, influences morphogenetic processes in living organisms, an area gaining increased attention alongside the role of mechanical forces in shaping cell behavior.
12 citations
,
October 1996 in “Dermatologic clinics” This review outlines the diagnostic criteria for congenital and hereditary hair shaft abnormalities and emphasizes the need to understand the weathering process in assessing these disorders.
36 citations
,
July 1988 in “Archives of Dermatological Research” Pili annulati is caused by a protein metabolism disorder affecting hair structure.
18 citations
,
September 1994 in “Clinical and Experimental Dermatology” This article describes a case of localized trichorrhexis nodosa in a patient with otherwise normal hair, highlighting the condition's response to trauma and diagnostic process but reporting no new clinical findings.
19 citations
,
February 2013 in “Journal of Investigative Dermatology” Touch domes in human skin are complex sensory structures not directly linked to hair.
2 citations
,
January 1987 in “PubMed” This study reported three related cases of woolly hair syndrome transmitted as a dominant autosomal trait, characterized by fine, frizzy hair and general hair thinning.
53 citations
,
March 2006 in “Biopolymers” This study suggests that increased amounts of less stable disulfide conformers in hair shafts may be linked to the brittleness observed in trichothiodystrophy.
11 citations
,
June 1974 in “Journal of Cutaneous Pathology” In this study, electron microscopy of follicular mucinosis showed severe cytoplasmic degeneration in hair follicles, with myelin figures and onion-like lamellar structures, but no indications of mucin release through degeneration or degradation were found.
3 citations
,
April 2011 in “Microscopy research and technique” This study found that hair from ovarian teratomas shares similar chemical composition and morphology with scalp hair, but differs in physical properties and cysteic acid bands.
68 citations
,
August 2012 in “Journal of the American Academy of Dermatology” This paper discusses the use of dermatoscopy as a fast, noninvasive technique for diagnosing hair shaft disorders and reports no new results; the authors highlight its advantages over traditional microscopy methods.
This report presents a rare case of lichen spinulosus in a 52-year-old woman, featuring hyperkeratotic follicular papules and a dense lymphohistiocytic infiltrate in affected skin areas.
12 citations
,
February 2011 in “Zenodo (CERN European Organization for Nuclear Research)” This research describes methods to analyze the mechanical properties and fracture characteristics of hair across different types and ages, using specialized tensile testing and imaging techniques, without reporting new results.
1 citations
,
March 2014 in “Journal of Innovative Optical Health Sciences” This study found that in mice, wool structure deteriorates as a malignant tumor develops, suggesting potential uses in cancer diagnostics.
1 citations
,
July 2015 in “Microscopy Research and Technique” In this study, researchers found that patients with Friedreich's ataxia exhibited more pronounced ultra-structural hair alterations compared to carriers, likely due to oxidative stress related to deficient frataxin expression.
41 citations
,
January 2014 in “Annals of Dermatology” This study found that dermoscopy showed distinctive patterns for different types of alopecia, supporting its clinical usefulness for diagnosing diseases with small round or oval hairless patches on the scalp.
33 citations
,
December 1982 in “Developmental Medicine & Child Neurology” The authors reviewed cases of six children with both hair-shaft abnormalities and neurological disorders, noting that such hair defects may indicate neurological conditions, including potentially treatable metabolic errors.
July 2025 in “Communications Biology” In this study, researchers used synchrotron X-ray imaging to examine rat vibrissa follicles, finding that despite variations in vibrissa length and follicle size, certain sensory structures remain consistent, suggesting specialized roles in sensory processing depending on the vibrissa type.
October 2023 in “Asian journal of pharmaceutical and clinical research” In this study, researchers used trichoscopy to establish standardized findings for normal hair and scalp characteristics in 360 healthy males, noting significant age-related differences in hair diameter variability and identifying potential pathological indicators like colored dots and scarring not present in healthy individuals.
February 1988 in “Journal of the American Academy of Dermatology”
January 2006 in “Seibutsu Butsuri” Curly and straight hair differ in how their internal fibers are arranged.
264 citations
,
October 1958 in “Archives of Dermatology” This report describes a 1949 case of a young girl with a rare congenital ectodermal defect causing unique hair fragility, which had not been previously documented in the literature.
62 citations
,
December 2008 in “Journal of structural biology” This study found that in naturally curved human scalp hairs, distinct arrangements of cell types on either side of the hair fiber contribute to its curvature.
44 citations
,
October 1990 in “Archives of Dermatological Research” The connective tissue around hair follicles changes structure throughout the hair cycle.
March 2026 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH” This case series reports three novel and atypical morphological patterns of alopecia areata, termed the central sparing, paw, and punctate patterns, highlighting their importance for dermatologists in improving diagnosis and management of the condition.