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    Did you mean Testosterone Production?
    Glossary Testosterone Production

    process by which the body generates the hormone testosterone

    Testosterone production, also known as testosterone synthesis or androgen production, refers to the process by which the body generates testosterone, a key male sex hormone. This process primarily occurs in the testes in men and in smaller amounts in the ovaries in women and the adrenal glands in both sexes. Testosterone plays a crucial role in the development of male reproductive tissues, the maintenance of muscle mass, bone density, and the regulation of libido. The production is regulated by the hypothalamus and pituitary gland through a feedback loop involving luteinizing hormone (LH).

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    1. Central 5-alpha reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary–adrenal axis response to restraint stress in adult male rats Brain Research · 2013 · 51 citations
    2. Oral Testosterone in Oil: Pharmacokinetic Effects of 5 Reduction by Finasteride or Dutasteride and Food Intake in Men International Journal of Andrology · 2006 · 22 citations
    3. Potential adverse effects of long-term testosterone therapy Baillière's clinical endocrinology and metabolism · 1998 · 72 citations
    4. Effects of the anti-androgen finasteride on 5α-reduction of androgens in the presence of progesterone in human gingival fibroblasts: modulatory actions of the alkaline phosphatase inhibitor levamisole Journal of Periodontal Research · 2000 · 9 citations
    5. Hair removal in hirsute women with normal testosterone levels: a randomized controlled trial of long-pulsed diode laser vs. intense pulsed light 2010 · 41 citations
    6. Reduction in the Free Androgen Index in Overweight Women After Sixty Days of a Low Glycemic Diet Experimental and clinical endocrinology & diabetes · 2024
    7. A Large Benign Adrenocortical Adenoma Cosecreting Testosterone and Cortisol JCEM case reports · 2024
    8. SAT383 Case Study: Impact of Weight Reduction and Oral Contraceptive Pills on Hyperandrogenism Journal of the Endocrine Society · 2023
    9. Comparison of a gonadotropin-releasing hormone agonist and a low dose oral contraceptive given alone or together in the treatment of hirsutism. The Journal of Clinical Endocrinology & Metabolism · 1995 · 62 citations
    10. INSULIN-LOWERING MEDICATIONS IN POLYCYSTIC OVARY SYNDROME Obstetrics and Gynecology Clinics of North America · 2000 · 39 citations
    11. Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases Current Medicinal Chemistry · 2016 · 11 citations
    12. Cosmetic Concerns Among Men Dermatologic Clinics · 2017 · 10 citations
    13. Androgen binding profiles of two distinct nuclear androgen receptors in Atlantic croaker (Micropogonias undulatus) The Journal of Steroid Biochemistry and Molecular Biology · 2000 · 58 citations
    14. Menopausal Acne – Challenges And Solutions DOAJ (DOAJ: Directory of Open Access Journals) · 2019
    15. A systematic review of antiandrogens and feminization in transgender women Clinical endocrinology · 2020 · 31 citations
    16. Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-<i>N</i>-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors Journal of Medicinal Chemistry · 2002 · 22 citations
    17. Hirsutism: a guide for the obstetrician and gynaecologist The Obstetrician & Gynaecologist · 2025
    18. CHAPTER 1 Facial Feminization Surgery: A Global Approach 2017
    19. Structure of human steroid 5α-reductase 2 with anti-androgen drug finasteride Research Square (Research Square) · 2020 · 4 citations
    20. Gender Surgery Beyond Chest and Genitals: Current Insurance Landscape Aesthetic Surgery Journal · 2019 · 15 citations
    21. Effect of <i>Eurycoma longifolia</i> Extract on Testosterone Synthesis in TM3 Leydig Cells under Oxidative Stress 2022 · 1 citations
    22. 5α-reduction of epitestosterone is catalysed by human SRD5A1 and SRD5A2 and increases androgen receptor transactivation The Journal of Steroid Biochemistry and Molecular Biology · 2024 · 14 citations
    23. CHRONIC TREATMENT REGIMENS FOR HIRSUTISM IN WOMEN: EFFECT ON BLOOD PRODUCTION RATES OF TESTOSTERONE AND ON HAIR GROWTH Clinical Endocrinology · 1975 · 29 citations
    24. Testosterone Induces Increase in Aquaporin (AQP)-1, 5, and 7 Expressions in the Uteri of Ovariectomized Rats The Journal of Membrane Biology · 2015 · 23 citations
    25. The injectable contraceptives depot medroxyprogesterone acetate and norethisterone enanthate substantially and differentially decrease testosterone and sex hormone binding globulin levels: A secondary study from the WHICH randomized clinical trial PLoS ONE · 2024 · 4 citations
    26. Effects of the use of finasteride on prostate volume and serum PSA in young patients Digital Library of Theses and Dissertations (Universidade de São Paulo) · 2015
    27. Hiperandrogenismo avanzado en una mujer postmenopáusica: Caso clínico Revista Medica De Chile · 2011 · 2 citations
    28. Steroid inhibitors of androgen-potentiated actions on skin 1983 · 4 citations
    29. Abstract 152 Indian Journal of Endocrinology and Metabolism · 2022
    30. Sa1389: LESSONS FROM HEPATITIS C TREATMENT DURING THE COVID-19 PANDEMIC: DECREASED RESOURCE UTILIZATION LEADS TO SIMILAR EFFICACY IN BRITISH COLUMBIA, CANADA Gastroenterology · 2022