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    Glossary Testosterone Metabolism

    process of breaking down and converting testosterone in the body

    Testosterone metabolism refers to the process by which the body breaks down and converts testosterone, a key male sex hormone, into other substances. This involves enzymes that transform testosterone into dihydrotestosterone (DHT) and estradiol, which play crucial roles in various bodily functions, including hair growth and sexual development. Understanding this process is important for addressing conditions like alopecia, where DHT can contribute to hair loss.

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    1. Testosterone metabolites differentially maintain adult morphology in a sexually dimorphic neuromuscular system Developmental Neurobiology · 2009 · 25 citations
    2. Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites Frontiers in Neuroendocrinology · 2020 · 18 citations
    3. Direct quantitative digital autoradiography of testosterone metabolites in the pilosebaceous unit: an environmentally advantageous trace radioactive technology Steroids · 1993 · 4 citations
    4. Testosterone metabolite nonessential for androgen effects Nature Reviews Endocrinology · 2012 · 2 citations
    5. DIABETE E DOLORE: EFFETTO TERAPEUTICO DEI METABOLITI DEL TESTOSTERONE Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) · 2014
    6. Anabolic and Metabolic Effects of Testosterone and Other Androgens: Direct Effects and Role of Testosterone Metabolic Products Endocrinology · 2017 · 2 citations
    7. Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men Advances in Experimental Medicine and Biology · 2017 · 31 citations
    8. Metabolic Syndrome, Hepatic Steatosis and Testosterone: A Matter of Sex Livers · 2024 · 7 citations
    9. Modification of testosterone levels with Piptadeniastrum africanum and Cordia plathytyrsa may influence metabolic parameters in Wistar rats Zenodo (CERN European Organization for Nuclear Research) · 2022
    10. Clinical and metabolic implications of obesity in prostate cancer: is testosterone a missing link? 2018 · 12 citations
    11. Persistent Poor Metabolic Profile in Postmenopausal Women With Ovarian Hyperandrogenism After Testosterone Level Normalization Journal of the Endocrine Society · 2019 · 8 citations
    12. Preparation of3H-labelled testosterone metabolites Journal of Labelled Compounds and Radiopharmaceuticals · 2007 · 2 citations
    13. Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System Androgens · 2021 · 1 citations
    14. Androgenic effect of testosterone and some of its metabolites in relation to their biotransformation in the skin. 1982 · 11 citations
    15. Testosterone protects female embryonic heart H9c2 cells against severe metabolic stress by activating estrogen receptors and up-regulating IES SUR2B The International Journal of Biochemistry & Cell Biology · 2012 · 24 citations
    16. The Role of Non-Aromatizable Testosterone Metabolite in Metabolic Pathways Physiological Research · 2011 · 21 citations
    17. Circulating testosterone and feather-gene expression of receptors and metabolic enzymes in relation to melanin-based colouration in the barn owl General and comparative endocrinology · 2017 · 14 citations
    18. Modification of testosterone levels with Piptadeniastrum africanum and Cordia plathytyrsa may influence metabolic parameters in Wistar rats World Journal of Advanced Research and Reviews · 2022
    19. Evaluation of dihydrotestosterone levels and total testosterone to dihydrotestosterone ratio with clinical symptoms and metabolic parameters in patients with polycystic ovary syndrome BMC Endocrine Disorders · 2025
    20. 892 Behavior of the two circulating androgens testosterone and DHEA and their main intracellular metabolites in an androgen-sensitive sebocyte cell line Journal of Investigative Dermatology · 2019
    21. Testosterone replacement in 49,XXXXY syndrome: andrological, metabolic and neurological aspects Endocrinology, diabetes & metabolism case reports · 2016 · 12 citations
    22. Total testosterone to dihydrotestosterone ratio assessed by LC-MS/MS predicts a worse metabolic profile not only in PCOS patients Ginekologia Polska · 2017 · 9 citations
    23. A Randomized Double-Blind Placebo-Controlled Pilot Trial on the Effects of Testosterone Undecanoate Plus Dutasteride or Placebo on Muscle Strength, Body Composition, and Metabolic Profile in Transmen The Journal of Sexual Medicine · 2021 · 7 citations
    24. Verstärkter Haarwuchs unter Langzeittokolyse mit Fenoterol** unter Berücksichtigung von Testosteron, Androstandiol, Cortisol und ACTH* Geburtshilfe und Frauenheilkunde · 1980 · 9 citations
    25. Impaired metabolic effects of metformin in men with early-onset androgenic alopecia Pharmacological Reports · 2021 · 4 citations
    26. No metabolic impact of surgical normalization of hyperandrogenism in postmenopausal women with ovarian androgen-secreting tumours Clinical Endocrinology · 2012 · 17 citations
    27. The differences between aromatizable and non-aromatizable androgens in relation to body composition and metabolic syndrome risk factors in men The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 8 citations
    28. Steroidomics for highlighting novel serum biomarkers of testosterone doping Bioanalysis · 2019 · 23 citations
    29. Testosterone Metabolism in Human Skin Cells in vitro and Its Interaction with Estradiol and Dutasteride Skin pharmacology and physiology · 2003 · 21 citations
    30. Metabolic study of androsta-1,4,6-triene-3,17-dione in horses using liquid chromatography/high resolution mass spectrometry 2015 · 17 citations