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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

PCOS is caused by both genetics and environmental factors like diet and obesity.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

The Rotterdam Study aims to understand various diseases in older adults.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.

Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Over one-third of women experience hair loss, with female-pattern hair loss being most common, and treatments include minoxidil and possibly hair transplantation.

Diffuse alopecia in women may be related to androgens and iron deficiency, and basic hormone and nutrient screening is useful.

The study found that Frontal Fibrosing Alopecia affects a broader age range of women and early treatment can help stop hair loss.

Many women in southern China have polycystic ovary syndrome, with some symptoms differing from Western women.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.