research Hormonal and Clinical Evaluation of Patients with Moderate Body Hair Growth
Women with moderate body hair have higher levels of certain hormones and may benefit from treatment that increases sex hormone-binding protein.
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research Diffuse Alopecia of the Scalp in Borderline-Lepromatous Leprosy in an Indian Patient
A neglected leprosy treatment led to rare scalp hair loss in an Indian woman, which improved with proper medication.
research Summaries of Papers
The document concludes that secondary syphilis cases are increasing and often misdiagnosed, pityriasis rubra pilaris can be distinguished from psoriasis by skin cell features, and different skin layers produce specific components during skin repair.
research Use of Metformin Versus Chromium Picolinate in the Management of Polycystic Ovarian Syndrome: A Randomized Controlled Clinical Trial
Chromium picolinate was better tolerated than metformin for PCOS with fewer side effects.
research In This Issue
Advancements in hair biology include new treatments and tools for hair growth and alopecia.
research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia
People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
research Abdominal Fat Quantity and Distribution in Women with Polycystic Ovary Syndrome and Its Relation to Insulin Resistance
Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.
research Lack of Efficacy of Finasteride in Postmenopausal Women with Androgenetic Alopecia
Finasteride doesn't effectively treat hair loss in postmenopausal women.
research Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp
Cells from balding scalps have more androgen receptors than cells from non-balding scalps.
research Global Adiposity Rather Than Abnormal Regional Fat Distribution Characterizes Women with Polycystic Ovary Syndrome
Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.
research The Role of Androgen and Androgen Receptor in Skin-Related Disorders
Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.
research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
research Immunohistochemical Localization of Types 1 and 2 5α-Reductase in Human Scalp
The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.
research Polymorphisms of the Androgen Receptor Gene and the Estrogen Receptor Beta Gene Are Associated with Androgen Levels in Women
Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
research The Hair Growth Promoting Effect of Asiasari Radix Extract and Its Molecular Regulation
Asiasari radix extract promotes hair growth and increases protein synthesis and cell proliferation.
research Finasteride
Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
research Female Gonadal Function Before and After Treatment of Acromegaly
Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.
research Androgenetic Alopecia in Children: Report of 20 Cases
AGA can occur in children with family history; early diagnosis and treatment important.
research Prostaglandin Metabolism in Human Hair Follicle
Human hair follicles can make and process prostaglandins, which may affect hair growth.
research Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism
Diane 35 plus finasteride is more effective for treating hirsutism.
research Effects of Dermatological Medications on Male Fertility
Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.
research Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes
People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
research Female Hirsutism: Pathophysiological Considerations and Therapeutic Implications
Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
research Association of Biochemical Hyperandrogenism with Type 2 Diabetes and Obesity in Chinese Women with Polycystic Ovary Syndrome
High androgen levels in Chinese women with PCOS are linked to a higher risk of diabetes and obesity.
research Steroidal 5α-Reductase and 17α-Hydroxylase/17,20-Lyase (CYP17) Inhibitors Useful in the Treatment of Prostatic Diseases
Certain drugs that block specific enzymes can help treat prostate diseases.
research Comparison of High-Dose Finasteride (5 mg/day) Versus Low-Dose Finasteride (2.5 mg/day) in the Treatment of Hirsutism
Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.
research Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss
Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.
research A Novel Finasteride 0.25% Topical Solution for Androgenetic Alopecia: Pharmacokinetics and Effects on Plasma Androgen Levels in Healthy Male Volunteers
New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.
research Finasteride in the Treatment of Hirsutism: New Therapeutic Perspectives
Finasteride effectively treats hirsutism in women, but more research needed for long-term results.