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Medical treatments like chemotherapy and radiotherapy can harm sperm production, so freezing sperm before treatment is important for men who want children later.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

Finasteride may effectively treat hair loss in Klinefelter Syndrome patients.

Lower finasteride doses had more side effects; dutasteride caused back pain; more research needed on post-finasteride syndrome.

Hormone treatment caused hair loss, finasteride helped regrowth.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Spironolactone treatment increases the amount of testosterone available in the body.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

The virus was not found in the semen and urine of a man who tested positive for COVID-19.