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Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Stump-tailed macaque best for researching hair loss causes and treatments.

Reproductive gynecologists are the main referrers for male infertility evaluations in North America.

Certain gene variations are not a major cause of male infertility in Nigerian men.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Finasteride can cause sexual problems and depression in young men.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Castration and finasteride lower urinary oxalate in male rats, potentially treating urolithiasis.

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Finasteride causes lasting fertility decrease in rats.

People undergoing chemotherapy need better support and information to cope with hair loss.

Finasteride for hair loss increases risk of long-lasting sexual dysfunction.

Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.