Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, researchers found that Hashimoto's thyroiditis patients, despite being in euthyroid status, experienced more severe extrathyroidal symptoms compared to healthy controls, and elevated thyroid antibodies were linked to lower health-related quality of life and increased inflammation.

This study reports that metreleptin treatment in a boy with congenital generalized lipodystrophy significantly improved metabolic complications and overall health outcomes during the first year of therapy.

This case report describes a rare instance of Hashimoto thyroiditis evolving into Graves' disease, emphasizing the potential for such transitions and the importance of early diagnosis and treatment.

This article discusses the history and understanding of Tay syndrome, recognizing it as a distinct condition related to ichthyotic erythroderma, mental retardation, and brittle hair but reports no new clinical results.

This study found that despite the persistence of aberrant double-negative T-cells, functional immune-competence was maintained after thymic transplantation in a patient with a rare FOXN1 mutation.

T cells affect skin cell genes in inflammatory diseases, and therapy can normalize these changes.

In this case study, a 5-year-old girl with alopecia areata and atopic dermatitis that were unresponsive to previous treatments achieved substantial improvement with long-term tofacitinib, highlighting its potential safety and efficacy in managing both conditions concurrently.

Increased Treg cells and IL-10 may help quick recovery in acute diffuse and total alopecia.

This study found that tofacitinib may be effective for treating pediatric rheumatic diseases, with especially promising results in patients with autoinflammatory diseases, arthritis and alopecia, and juvenile dermatomyositis.

Enhancing Tregs can protect against alopecia areata.

This study reports a case of a patient with neuromyelitis optica spectrum disorders treated with eculizumab who developed fatal sepsis after insulin resistance emerged.

In this review, researchers summarized findings from clinical studies on mesenchymal stem cells for diabetes treatment, noting their potential but also highlighting challenges like small sample sizes and the need for standardization in preparation and delivery methods.

This study found that in biopsied skin samples of alopecia areata, a lower anagen/telogen ratio was associated with increased T cell infiltration, and enhancing the PD-1/PD-L1 axis may inhibit CD8+T cell infiltration and improve the condition.

This study observed that patients with type 2 diabetes and sensorineural hearing loss exhibited significantly higher levels of peripheral myelin protein 22, particularly in those with microangiopathies, suggesting demyelinating processes in the auditory system.

This study found that mice lacking REDD1 experienced an expansion of dermal white adipose tissue through both hypertrophy and hyperplasia, suggesting a potential therapeutic target for skin adipogenesis regulation.

This study introduced an innovative nanozyme system called MCP@G, which was shown to improve diabetic wound healing in rats by alleviating mitochondrial oxidative stress, enhancing fibroblast migration, and promoting blood vessel and hair follicle regeneration, offering a promising approach for treating challenging diabetic wounds.

This study observed that while hair glucocorticoids were linked to type 2 diabetes, there was no social gradient in glucocorticoid levels among different socioeconomic groups, suggesting these biomarkers may not significantly contribute to understanding socioeconomic health disparities in diabetes.

Some people with chronic hair loss may have thyroid autoimmunity.

This study found that patients with myotonic dystrophy type 1 had higher numbers of nevi, dysplastic nevi, melanomas, and pilomatrixomas compared to age- and sex-matched controls.

In this study, researchers found that topical application of the diabetes medication Sitagliptin in mice accelerates hair follicle regeneration and reduces fibrosis, suggesting it could be repurposed to treat hair loss conditions like alopecia.

Early hair loss might indicate diabetes and heart risks, especially in those under 45.

A rare pancreatic tumor caused a woman's male-like features, treated successfully with surgery and medication.

This review explores the complex, context-specific roles of Wnt/β-catenin signaling in six diabetic complications and suggests that targeted modulation could improve both pathological and functional outcomes.

This case study documents a 55-year-old male with advanced NSCLC who experienced toe-predominant paronychia and a papulopustular rash following dacomitinib treatment, with the causality tools indicating a "probable" link, yet the therapy continued successfully without dosage alteration.

This review described how skin inspection plays a critical role in diagnosing serious endocrine disorders by identifying various cutaneous manifestations linked to conditions like insulin resistance, diabetes, and hyper and hypothyroidism, highlighting its significance in early, life-saving detection.

This review discusses the dermatologic side effects and potential therapeutic benefits of GLP-1 receptor agonists, such as facial fat loss and wound healing, emphasizing the need for further research.

CTP-543 significantly improved eyebrow and eyelash regrowth and patient satisfaction in adults with alopecia areata.

This article discusses alopecia areata as a potential model for studying T cell-dependent autoimmune diseases and reports no new experimental findings.

In this study, researchers found that metformin improved glycaemic control and other metabolic parameters in non-diabetic patients on glucocorticoid treatment, also reducing pneumonia risk and hospital admissions, suggesting a potential advantage for routine use in this population.