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Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

The 2006 editorial concluded that immunotherapy was advancing with new drugs, focusing on specific biological therapies and convenient oral treatments, and highlighted the importance of partnerships and new regulations in the field.

Finasteride helps female-pattern hair loss.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Frontal fibrosing alopecia is a hair loss condition in postmenopausal women, similar to lichen planopilaris, with ineffective treatments.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Low iron levels may be linked to some types of hair loss in women.

Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

Probiotic bacteria improved skin and hair health in aged mice.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.

Both ruxolitinib and tofacitinib are effective and safe for treating severe alopecia areata, but relapses are common.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

Topical immunotherapy, especially with DPCP, is effective for treating severe alopecia areata.

The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.