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    Glossary T cells

    specialized white blood cells crucial for immune response

    T cells, also known as T lymphocytes, are a type of white blood cell that plays a crucial role in the immune system. They help protect the body from infections and may also be involved in autoimmune conditions, where the immune system mistakenly attacks the body's own tissues. T cells can be further categorized into different types, such as helper T cells, which assist other immune cells, and cytotoxic T cells, which directly kill infected or cancerous cells.

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    Research 30 of 1000+

    1. Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation Nature communications · 2016 · 155 citations
    2. Human αβ and γδ T Cells in Skin Immunity and Disease Frontiers in immunology · 2018 · 83 citations
    3. T helper 17 cell/regulatory T-cell imbalance in hidradenitis suppurativa/acne inversa: the link to hair follicle dissection, obesity, smoking and autoimmune comorbidities 2018 · 66 citations
    4. Hair Follicle Mesenchyme-Associated PD-L1 Regulates T-Cell Activation Induced Apoptosis: A Potential Mechanism of Immune Privilege Journal of Investigative Dermatology · 2013 · 53 citations
    5. Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis American journal of human genetics · 2019 · 53 citations
    6. The imbalance between Type 17 T-cells and regulatory immune cell subsets in psoriasis vulgaris Frontiers in Immunology · 2022 · 49 citations
    7. High-throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in alopecia areata JCI insight · 2018 · 46 citations
    8. Recurrence of cutaneous T‐cell lymphoma post viral vector COVID‐19 vaccination Journal of the European Academy of Dermatology and Venereology · 2021 · 35 citations
    9. Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1 Development · 2010 · 34 citations
    10. The Effects of Androgens on T Cells: Clues to Female Predominance in Autoimmune Liver Diseases? Frontiers in immunology · 2020 · 34 citations
    11. <i>In vivo </i>CD44‐CD49d complex formation in autoimmune disease has consequences on T cell activation and apoptosis resistance European Journal of Immunology · 2006 · 33 citations
    12. Diverse Role of OX40 on T Cells as a Therapeutic Target for Skin Diseases Journal of Investigative Dermatology · 2023 · 30 citations
    13. Alopecia areata as a model for T cell‐dependent autoimmune diseases Experimental Dermatology · 2012 · 28 citations
    14. Psoriasis patients demonstrate HLA-Cw*06:02 allele dosage-dependent T cell proliferation when treated with hair follicle-derived keratin 17 protein Scientific Reports · 2018 · 27 citations
    15. Diffuse alopecia areata is associated with intense inflammatory infiltration and CD8+ T cells in hair loss regions and an increase in serum IgE level Indian Journal of Dermatology, Venereology and Leprology · 2012 · 24 citations
    16. Low-Dose IL-2 for Treating Moderate to Severe Alopecia Areata: A 52-Week Multicenter Prospective Placebo-Controlled Study Assessing its Impact on T Regulatory Cell and NK Cell Populations 2020 · 22 citations
    17. Phenotypic Analysis of T-Cells in Extensive Alopecia Areata Scalp Suggests Partial Tolerance 2005 · 21 citations
    18. Alopecia areata but not androgenetic alopecia is characterized by a restricted and oligoclonal T-cell receptor-repertoire among infiltrating lymphocytes Journal of Cutaneous Pathology · 1997 · 19 citations
    19. Distinguishing diffuse alopecia areata (AA) from pattern hair loss (PHL) using CD3+ T cells Journal of The American Academy of Dermatology · 2016 · 19 citations
    20. T-Regulating Hair Follicle Stem Cells Immunity · 2017 · 14 citations
    21. MmuPV1 infection and tumor development of T cell-deficient mice is prevented by passively transferred hyperimmune sera from normal congenic mice immunized with MmuPV1 virus-like particles (VLPs) Experimental and molecular pathology · 2016 · 14 citations
    22. Induction of T cell exhaustion by JAK1/3 inhibition in the treatment of alopecia areata Frontiers in immunology · 2022 · 13 citations
    23. Evaluation of platelet-rich plasma on hair regrowth and lesional T-cell cytokine expression in alopecia areata: A randomized observer-blinded, placebo-controlled, split-head pilot study Journal of The American Academy of Dermatology · 2020 · 9 citations
    24. Androgenetic alopecia may be associated with weaker COVID-19 T-cell immune response: An insight into a potential COVID-19 vaccine booster Medical Hypotheses · 2020 · 9 citations
    25. T-cell “induced-self” MHC class I/peptide complexes may enable “de novo” tolerance induction to neo-antigens occurring outside of the thymus Experimental dermatology · 2016 · 8 citations
    26. T-Cell Reconstitution after Thymus Xenotransplantation Induces Hair Depigmentation and Loss 2013 · 7 citations
    27. Direct T-cell effects of minoxidii Clinics in Dermatology · 1988 · 7 citations
    28. CD80CD86 deficiency disrupts regulatory CD4+FoxP3+T cell homoeostasis and induces autoimmune-like alopecia Experimental dermatology · 2017 · 6 citations
    29. Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases International journal of molecular sciences · 2023 · 6 citations
    30. Single-cell analysis of temporal immune cell dynamics in alopecia areata reveals a causal role for clonally expanded CD8+ T cells in disease Cell Reports · 2025 · 4 citations