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    Glossary Systemic Antiandrogens

    medications that reduce male hormone effects body-wide

    Systemic antiandrogens are medications that reduce the effects of androgens (male hormones) throughout the entire body. They are commonly used to treat conditions like androgenic alopecia (hair loss), prostate cancer, and severe acne by blocking androgen receptors or inhibiting androgen production. These therapies can be crucial for managing hormone-related disorders and are often referred to as systemic anti-androgen therapy.

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    1. Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: Relation of their systemic activity to the formation of a common metabolite The Journal of Steroid Biochemistry and Molecular Biology · 1994 · 16 citations
    2. Spironolactone is an effective and well tolerated systemic anti-androgen therapy for hirsute women Oxford University Research Archive (ORA) (University of Oxford) · 1989
    3. Spironolactone is an Effective and Well Tolerated Systemic Antiandrogen Therapy for Hirsute Women* The Journal of Clinical Endocrinology & Metabolism · 1989 · 78 citations
    4. Pharmacology of Anti-androgens in the Skin Handbook of experimental pharmacology · 1989 · 1 citations
    5. Topical antiandrogens in the treatment of male-pattern baldness Clinics in dermatology · 1988 · 10 citations
    6. Clascoterone: a new topical antiandrogen agent. Prospects in Pharmaceutical Sciences · 2025
    7. Mesotherapy with dutasteride for androgenetic alopecia: a concise review of the literature European Journal of Dermatology · 2023
    8. Hair Loss and Androgen’s Role in the Era of COVID-19 International Journal of Biomedicine · 2022
    9. Systemic treatment options for androgenic alopecia Lithuanian University of Health Sciences · 2026
    10. Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity Journal of Investigative Dermatology · 1995 · 37 citations
    11. Acne and Systemic Disease Medical Clinics of North America · 2009 · 76 citations
    12. Anti-androgen therapy for the treatment of female pattern hair loss: a clinical review of current and emerging therapies Journal of the American Academy of Dermatology · 2025
    13. RU 58841, a new specific topical antiandrogen: A candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism The Journal of Steroid Biochemistry and Molecular Biology · 1994 · 49 citations
    14. Dermatosis associated with menopause Journal of Mid-life Health · 2014 · 10 citations
    15. Managing hair loss Current Therapeutics · 1998
    16. S127 Regulation of hair growth 1997
    17. Die Menopause und ihre Auswirkungen auf Haut und Haare Gynäkologische Endokrinologie · 2023
    18. Faculty Opinions recommendation of Prospective cohort study on the effects and tolerability of flutamide in patients with female pattern hair loss. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2013
    19. Female pattern hair loss Journal of The American Academy of Dermatology · 2001 · 226 citations
    20. Hair Loss in Women Seminars in Cutaneous Medicine and Surgery · 2009 · 81 citations
    21. Alopecia and Hirsuties Drugs · 1988 · 15 citations
    22. The psychological and aesthetic impact of age‐related hair changes in females Journal of Cosmetic Dermatology · 2019 · 6 citations
    23. THERAPEUTIC APPROACHES TO THE MANAGEMENT OF COMMON BALDNESS International Journal of Clinical Practice · 1999 · 2 citations
    24. Common data base programs for accelerator physics Therapeutische Umschau. Revue thérapeutique · 1984 · 1 citations
    25. Management OF Patients with Polycystic Ovary Syndrom Neliti · 2025
    26. Medical Management Options for Hair Loss Springer eBooks · 2011
    27. Hypertrichosis and hirsutism Therapeutische Umschau · 2002
    28. Medications and hair transplantation Cambridge University Press eBooks · 2009
    29. Hair loss in women 2011
    30. Comment on “Hidradenitis suppurativa in children treated with finasteride-A case series” Pediatric Dermatology · 2018 · 1 citations