17 citations
,
April 2006 in “Brain Research” This study found that stimulation with certain neurotransmitters and hormones suggests the involvement of 5α-reduced neurosteroids in glial cell differentiation in rat C6 glioma cells.
6 citations
,
September 2020 in “Advanced Biology” This study found that using the OptoTrkA system to control TrkA activity with blue light enhanced proliferation, migration, and differentiation of hair-follicle-derived stem cells into neuronal and glial cells.
40 citations
,
March 1991 in “Journal of Investigative Dermatology” 25 citations
,
October 2005 in “PubMed” This study found that keratin 19 and nuclear galectin-1 binding can transiently express in interfollicular epidermal cells after adhesion, suggesting keratin 19 should not be solely used as a stem cell activity marker.
14 citations
,
October 2018 in “Brain Research Bulletin” This article reviews the role of exosomes in promoting axonal regeneration and discusses recent findings on how exosome-borne molecules might influence the PTEN-mTOR pathway in injured neurons; it reports no new experimental results.
11 citations
,
July 2021 in “Physiologia Plantarum” In this study, the gene SlPHL1 was identified as a transcription factor in tomatoes that enhances phosphate starvation responses by upregulating specific genes.
5 citations
,
September 2021 in “Journal of Molecular Histology” In this study, the researchers identified LHX2 as a specific marker for hair follicle placodes, differentiating them from eccrine sweat gland placodes through double immunofluorescence staining.
61 citations
,
May 2016 in “Scientific reports” This study found that IMT-P8, a novel cell-penetrating peptide, effectively facilitated the dermal delivery of proteins and peptides in mouse skin and cell lines, suggesting potential for topical applications in cosmetics and skin diseases.
25 citations
,
April 2012 in “Acta Biomaterialia” This study observed that NSPC predominantly differentiated into neurons when exposed to serum fractions with molecules under 100 kDa, particularly with biomaterial and fibronectin, in the presence of basic fibroblast growth factor.
April 2009 in “The FASEB Journal” This study demonstrated that a keratin gel promotes nerve regeneration across critical defects in rabbit models, showing improved nerve conduction and muscle action potential compared to control treatments.
41 citations
,
February 2005 in “Experimental Cell Research” This study suggests that the MAEG protein may facilitate epithelial–mesenchymal interactions during hair follicle development by binding to RGD-binding integrins like α8β1.
4 citations
,
April 2025 in “Frontiers in Immunology” This article discusses the potential of extracellular vesicles for developing precise psychiatric therapies and the need for interdisciplinary collaboration, but reports no new clinical results.
December 1991 in “Annals of the New York Academy of Sciences” 22 citations
,
February 2007 in “Developmental neurobiology” This study found that variations in Kv1 channel gene expression in the electric organ of Sternopygus correlate with sex differences and individual variations in their electric communication signals.
18 citations
,
December 1992 in “Journal of Cutaneous Pathology” This study observed that lectin-binding patterns in skin appendage tumors reveal differences in sweat gland tumors compared to normal tissues, but pilosebaceous tumors maintained a similar lectin-binding pattern to their corresponding normal structures.
2 citations
,
January 2025 in “Journal of Nanobiotechnology” This study demonstrated that genetically engineered, ATP-responsive nanozymes effectively reduce cardiac fibrosis by targeting activated cardiac fibroblasts, resulting in decreased myofibroblast accumulation and improved cardiac function, suggesting that this approach has significant potential for therapeutic applications.
13 citations
,
November 2012 in “PLoS ONE” This study identified a novel recessive mutation in mice causing lethal congenital lamellar ichthyosis, with skin and hair follicle alterations similar to human congenital ichthyoses, linked to a specific genetic defect affecting Fatp4.
30 citations
,
August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that TGase 3 may contribute to hair fiber scaffolding by forming specific isopeptide bonds between keratin intermediate filaments and keratin-associated proteins.
April 2026 in “Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy” This research found that nod factor can induce root hair reorientation and gene expression in Medicago truncatula with as little as a single molecule, implicating heterotrimeric G-protein signaling in this process.
1 citations
,
January 2025 in “Proceedings of the National Academy of Sciences” This study used cryoelectron microscopy to unveil the structure of LPA-bound human LPAR6, revealing unique ligand binding and recognition modes distinct from LPAR1, which may aid in designing targeted compounds for hair loss and cancer.
This study found that the Arabidopsis thaliana protein Formin 2 localizes to plasmodesmata and is crucial for regulating their permeability by anchoring actin filaments, which affects virus susceptibility.
80 citations
,
June 2002 in “Molecular Biology of the Cell” This study found that type II keratins in proliferating epithelial tissues are phosphorylated at a conserved motif during mitosis and stress, impacting keratin solubilization and reorganization.
CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.
25 citations
,
October 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study characterized the mouse profilaggrin gene, finding it structurally identical to its human counterpart, and noted differences in protein-coding regions that could impact epidermal differentiation.
5 citations
,
August 2005 in “Anatomy and Embryology” This study found that concentrated clusters of noradrenergic nerve fibers form a longitudinal linear system in rat skin, particularly innervating arrector pili muscles.
12 citations
,
August 1988 in “Histopathology” This case report describes a giant pigmented tumor of the scalp in a 47-year-old woman and suggests a possible dual origin involving neural crest differentiation.
53 citations
,
April 1985 in “Developmental Biology” Fibronectin and other basement membrane components increase during hair growth and decrease during rest.
22 citations
,
January 1990 9 citations
,
July 2014 in “PubMed” This study found distinct localization patterns of S100 family proteins in hair follicles, suggesting their differential roles in normal hair follicle physiology.