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Elastic Net DNA methylation clocks are inaccurate for predicting age and health status; a "noise barometer" may better indicate aging and disease.

Frailer men have a higher risk of worsening prostate problems and serious health events needing hospital care.

Blood tests for tumor cells could improve prostate cancer diagnosis and treatment; hair loss severity linked to a gene affecting prostate conditions.

The document concludes that a new biosensor can efficiently detect prostate cancer cells and that standardized referrals help find significant cancers effectively.

CEC levels may be a useful marker for predicting prostate cancer progression.

Gene variation affects prostate issues and hair loss.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Blood removal and birth control pills both helped with hormone levels in women with PCOS, but birth control was better for regular periods and blood removal had fewer side effects.

Metformin improved insulin resistance and BMI in overweight Taiwanese women with PCOS, and a 2-hour insulin test may be a good screening tool.

Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.

Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.

High testosterone increases heart disease risk in women with PCOS.

The document emphasizes the importance of ongoing research and ethical considerations in genome editing and cellular reprogramming.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Finasteride lowers risk of urinary issues and surgery by over 50% in 4 years.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.