78 citations,
October 2020 in “Experimental Dermatology” Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
77 citations,
March 2021 in “Nature” Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
76 citations,
January 2017 in “World Journal of Stem Cells” Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.
72 citations,
January 2011 in “Current Pharmaceutical Design” S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
72 citations,
April 2008 in “The Journal of urology/The journal of urology” Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.
67 citations,
September 1997 in “Dermatologic Surgery” The document concludes that good cosmetic outcomes in hair transplantation depend on the surgeon's artistic skill and careful planning.
66 citations,
May 2021 in “Science Advances” Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
66 citations,
June 2018 in “International Journal of Women's Dermatology” No cure for female pattern hair loss, but various effective treatments exist.
66 citations,
June 2018 in “British Journal of Dermatology” European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.
65 citations,
March 2018 in “Journal of Dermatological Science” Skin problems can be caused or worsened by physical forces and pressure on the skin.
65 citations,
March 2016 in “Lasers in Medical Science” Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.
65 citations,
May 2010 in “Current Women's Health Reviews” Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.
64 citations,
March 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
63 citations,
May 2011 in “Clinical cancer research” The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
61 citations,
June 2018 in “Proceedings of the National Academy of Sciences of the United States of America” Light can turn on hair growth cells through a nerve path starting in the eyes.
60 citations,
July 2020 in “ACS Nano” Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.
59 citations,
February 2021 in “BMJ” High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.
59 citations,
August 2018 in “The oncologist” Some breast cancer patients still experience hair loss three years after chemotherapy, especially with taxane-based treatments.
59 citations,
September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
58 citations,
November 2013 in “Journal of Innovative Optical Health Sciences” Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.
58 citations,
September 2012 in “Dermatologic Clinics” Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.
57 citations,
July 2016 in “The Journal of Sexual Medicine” 5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.
57 citations,
March 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
55 citations,
April 2017 in “Experimental Dermatology” The document describes a way to isolate and grow human hair follicle cells in 3D to help study hair growth.
55 citations,
October 2009 in “Clinics in Plastic Surgery” Burn reconstruction improves with new techniques, materials, and tissue engineering.
53 citations,
October 2018 in “Aesthetic Surgery Journal” Google Trends data on facial cosmetic procedures matches actual surgery numbers, showing it can help plastic surgeons understand public interest.
53 citations,
January 2012 in “Fertility and Sterility” Women with PCOS are more likely to have sleep apnea, mainly if they are obese.
51 citations,
January 2012 in “Annals of Dermatology” Asian hair loss differs from Europeans; consider individual needs and psychological well-being for treatment.
50 citations,
March 2017 in “PeerJ” Using finasteride or dutasteride may cause long-lasting erectile dysfunction.
49 citations,
September 2012 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.