42 citations
,
April 2012 in “Seminars in Oncology” This review discusses the skin side effects associated with targeted cancer therapies and reports no new clinical results; it emphasizes the need for empirical management based on expert opinion.
45 citations
,
January 2007 in “Journal of Clinical Oncology” This case report identifies hand-foot and stump syndrome as a potential side effect of sorafenib therapy in a 47-year-old man with a leg amputation.
11 citations
,
December 2013 in “Clinical and Experimental Dermatology” This article reviews the use of sorafenib, a multikinase inhibitor, for treating certain carcinomas, noting that cutaneous toxicity during treatment may indicate successful antitumor activity; however, it reports no new clinical results.
508 citations
,
June 2009 in “Current drug metabolism” This review details the skin and hematological toxicities of tyrosine kinase inhibitors like erlotinib, gefitinib, and imatinib, and highlights ongoing concerns about cardiac toxicity, reporting no new clinical findings.
March 2014 in “Journal of The American Academy of Dermatology” Reflectance confocal microscopy can noninvasively diagnose onychomatricoma by showing unique features different from healthy nails or nail fungus.
December 2016 in “John Wiley & Sons, Ltd eBooks” This chapter reviews disorders of skin appendages including miliaria, acne, and alopecia, providing guidance on management and treatment but does not present new clinical findings.
2 citations
,
October 2021 in “Journal of skin and stem cell” This study observed that nail abnormalities often indicate underlying dermatological or systemic conditions, with psoriasis and infections being the most common causes among patients.
8 citations
,
February 2012 in “International Journal of Dermatology” This review discusses skin problems common among long-distance runners and outlines helpful treatments, without presenting new clinical results.
2 citations
,
August 2022 in “Cutis” This article suggests that nail abnormalities might occur temporarily after COVID-19 vaccination, but they are self-limiting and should not deter individuals from getting vaccinated.
16 citations
,
March 2013 in “JAMA Dermatology” This case study describes a 33-year-old woman with chronic myelogenous leukemia who developed nonscarring alopecia after starting nilotinib therapy, linked to perifollicular inflammation.
15 citations
,
December 2014 in “Dermatology and therapy” This study reports that sorafenib-associated facial acneiform eruption, mimicking chloracne, is a rare cutaneous adverse event which improved upon reducing or discontinuing the drug.
September 2010 in “Institutional Repositories DataBase (IRDB)” Sorafenib can cause a temporary skin condition that goes away after stopping the drug.
17 citations
,
February 2012 in “Cutaneous and Ocular Toxicology” This study found that xerosis and pruritus are prevalent in patients with chronic renal failure undergoing hemodialysis, highlighting the importance of early recognition of skin issues to alleviate discomfort and reduce complications.
September 2023 in “Cureus” This study at B.J. Medical College and Civil Hospital highlighted an extensive range of nail disorders, with onychomycosis being the most common, and emphasized the importance of nails in diagnosing both dermatological and systemic conditions.
2 citations
,
May 2009 in “Medicine” This review discusses skin appendages like hair and nails as indicators of local and systemic pathologies, emphasizing conditions such as inflammatory diseases and infections, but reports no new clinical findings.
44 citations
,
August 2010 in “Lupus” This article reviews the characteristics and classification criteria of cutaneous lupus erythematosus and reports no new clinical findings.
This review discusses various skin-related conditions affecting hair and nails, highlighting associations with systemic pathologies but reports no new clinical findings.
January 2018 in “Elsevier eBooks” Different nail disorders are treated by targeting their specific causes and using appropriate medications or protective measures.
7 citations
,
May 2014 in “Clinical practice” This article reviews drug-induced hair and nail disorders and discusses their clinical recognition, underlying mechanisms, and potential treatment strategies, without presenting new research findings.
Robotic-assisted hair transplant is effective and less painful, but needs more evaluation for long-term results.
March 2014 in “Journal of The American Academy of Dermatology” Vitamin D deficiency is common in temporary hair loss, and stress is often a suspected cause.
March 2014 in “Journal of The American Academy of Dermatology” Tavaborole is a safe and effective toenail fungus treatment, with the 5% solution being the best option.
1 citations
,
December 2016 in “Journal of Evolution of Medical and Dental Sciences” This study found significant associations between pruritus and elevated parathormone levels, and xerosis and elevated serum creatinine levels, in chronic kidney disease patients undergoing haemodialysis.
30 citations
,
August 2010 in “American Journal of Clinical Dermatology” This article reviews eyelash elongation as a side effect of EGFR inhibitors in cancer treatment, finding that the condition is typically not severe and may be managed by trimming.
28 citations
,
December 2006 in “Clinical lung cancer” This review outlines various non-rash skin toxicities associated with novel targeted anticancer therapies and provides guidelines for their early diagnosis and management, but reports no new clinical results.
19 citations
,
October 2011 in “Clinics in Dermatology” This review discusses the cutaneous side effects of chemotherapy, noting that they frequently involve changes to skin, hair, and nails, and reports no new results.
18 citations
,
March 2004 in “Clinics in Dermatology” This review discusses recent advances in understanding the cellular, molecular, and genetic factors contributing to lupus erythematosus and reports no new experimental findings.
3 citations
,
November 2018 in “Oncology issues” This article discusses the emerging field of supportive oncodermatology, which collaborates between oncology and dermatology to address skin-related side effects of cancer treatments, and reports no new clinical results.
1 citations
,
January 2010 in “Elsevier eBooks” Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.
In this case report, a patient on low-dose sorafenib for hepatocellular carcinoma developed a rare and severe facial acneiform eruption without other skin side effects, which improved only minimally with topical treatment.