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Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Stem cell self-renewal is complex and needs more research for full understanding.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.