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Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Using the eye pressure medication latanoprost can cause excessive hair growth and darker eyelashes on the treated eye.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Noggin is necessary to start the hair growth phase in skin after birth.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Androgens can both increase and decrease hair growth in different parts of the body.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Lactate production is important for activating hair growth stem cells.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Finasteride effectively treats frontal hair loss with few side effects.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.