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    Did you mean Neurosteroid Synthesis?
    Glossary Neurosteroid Synthesis

    Neurosteroid synthesis refers to the production of steroid hormones within the brain and nervous system, which can influence various physiological processes, including mood, cognition, and stress response. In the context of hair loss, neurosteroids may play a role in modulating hair follicle biology and the hair growth cycle, particularly through their effects on androgen receptors and local hormonal balance. Key distinguishing characteristics of neurosteroids include their ability to rapidly affect neuronal function and their synthesis from cholesterol or other steroid precursors within the central nervous system.

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    1. Intratumoral <i>De Novo</i> Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors Cancer research · 2011 · 402 citations
    2. Synthesis of Spiro[cyclohexane-1,2?-[2H]indene] derivatives as inhibitors of steroid 5?-reductase Helvetica Chimica Acta · 1995 · 8 citations
    3. Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-<i>N</i>-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors Journal of Medicinal Chemistry · 2002 · 22 citations
    4. Synthesis of phenanthridin-3-one derivatives: Non-steroidal inhibitors of steroid 5-α-reductase Tetrahedron Letters · 1995 · 20 citations
    5. Synthesis, Biological Evaluation and Molecular Docking of Avicequinone C Analogues as Potential Steroid 5α-Reductase Inhibitors Chemical & Pharmaceutical Bulletin · 2017 · 13 citations
    6. Synthesis and Biological Evaluation of 4-(4-(Alkyl-and Phenylaminocarbonyl)benzoyl)benzoic Acid Derivatives as Non-steroidal Inhibitors of Steroid 5α-Reductase Isozymes 1 and 2 Archiv Der Pharmazie · 2002 · 8 citations
    7. Local synthesis and effect of sex steroids in human skin and the hair follicle and hormonal effects on the wound healing response Padua Research Archive (University of Padua) · 2011
    8. Synthesis of mimics of steroid A ring as potential enzyme inhibitors Research Repository (Kingston University London) · 2002
    9. Sex steroid synthesis in human skin in situ: The roles of aromatase and steroidogenic acute regulatory protein in the homeostasis of human skin Molecular and Cellular Endocrinology · 2012 · 46 citations
    10. Ovine placental steroid synthesis and metabolism in late gestation† Biology of reproduction · 2018 · 9 citations
    11. Synthesis and 5α-Reductase Inhibitory Activity of C21 Steroids Having 1,4-diene or 4,6-diene 20-ones and 4-Azasteroid 20-Oximes Molecules · 2011 · 186 citations
    12. FACILE WATER MEDIATED SYNTHESIS OF FINASTERIDE FORM-I, AN AZAANDROSTANE STEROID Heterocyclic Communications · 2007 · 1 citations
    13. Natural Product-Inspired Bis(trifluoromethyl) Phenyl Hydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitors of Human Steroid 5α-Reductase Type-1: Synthesis, <i>In Vitro</i>, and <i>In Silico</i> Studies ACS Omega · 2025
    14. Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research Journal of Neuroendocrinology · 2015 · 123 citations
    15. Estro-progestogen combinations: Effect on sex Steroid Binding Protein (SBP) synthesis Steroids · 1988 · 2 citations
    16. Synthesis and Study of Some 17a-aza-D-homo Steroids as 5α-Reductase Inhibitors Current Drug Discovery Technologies · 2020 · 1 citations
    17. Natural Product-InspiredBis(trifluoromethyl) PhenylHydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitorsof Human Steroid 5α-Reductase Type-1: Synthesis, <i>InVitro</i>, and <i>In Silico</i> Studies OPAL (Open@LaTrobe) (La Trobe University) · 2025
    18. Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates General and Comparative Endocrinology · 2020 · 21 citations
    19. The profile of steroid hormones in human fetal and adult ovaries Reproductive Biology and Endocrinology · 2024 · 11 citations
    20. Androgen Receptors and Androgen-Dependent Initiation of Protein Synthesis in the Prostate Vitamins and hormones · 1976 · 59 citations
    21. Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells American journal of physiology. Cell physiology · 2006 · 56 citations
    22. Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts The Journal of Steroid Biochemistry and Molecular Biology · 2009 · 57 citations
    23. Thiohydrazides in the Synthesis of Functionalized Extranuclear Heterosteroids 2023
    24. Novel 5α-Reductase Inhibitors:  Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids Journal of Medicinal Chemistry · 2005 · 18 citations
    25. Synthesis of 11α-hydroxyprogesterone hartens Steroids · 1989 · 7 citations
    26. Synthesis and Pharmacological Evaluation of New 16-Methyl Pregnane Derivatives. 2002 · 18 citations
    27. Inhibition of neurosteroid synthesis increases asphyxia-induced brain injury in the late gestation fetal sheep Neuroscience · 2007 · 100 citations
    28. Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System Androgens · 2021 · 1 citations
    29. Disruptors of Androgen Action and Synthesis Elsevier eBooks · 2015 · 1 citations
    30. New Synthesis of Finasteride Chinese Journal of Pharmaceuticals · 2003 · 1 citations