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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

Sex hormones, especially androgens, play a key role in causing acne.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

Trilostane helped a cat with a hormone issue but the cat later died from a kidney infection.

A patient produced cortisol after adrenalectomy, possibly due to residual tissue or other body parts making steroids.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Glioblastoma cells can make androgens, which might help the tumor grow.

Dogs with sex hormone imbalances may not drink or pee a lot but often lose hair on their body and can have reproductive system issues.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.

A 68-year-old woman developed male traits due to a tumor in her ovary, which was removed, returning her hormone levels to normal.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Autism's genetics are linked with early age of puberty and less hair loss, but not with hormone levels or polycystic ovary syndrome.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.