September 2025 in “Clinical Cosmetic and Investigational Dermatology” This study in Jordan found that topical corticosteroid use is common and often involves creams obtained without prescriptions, with only 61.3% of users aware of potential side effects, highlighting a need for better public education and regulation to prevent misuse.
1 citations
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April 2018 in “Our Dermatology Online” Trichoscopy can detect early signs of steroid overuse on the scalp, suggesting a need for non-steroidal treatments.
13 citations
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October 2015 in “Journal of the European Academy of Dermatology and Venereology” The document concludes that early recognition and appropriate treatment of red scalp, red ear, and red scrotum syndromes can lead to remission.
June 2026 in “Barind Medical College Journal” In this study, researchers examined 1,000 South Asian patients misusing topical corticosteroids for dermatophytosis and found that this misuse resulted in atypical, chronic, and recurrent fungal infections called steroid-modified dermatophytosis, often involving extensive and atypical skin presentations.
5 citations
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January 2015 in “Case reports in medicine” In this case report, a novel missense mutation c.1360G>C (p.Ala454Pro) in the MBTPS2 gene was identified in a boy with typical IFAP syndrome and severe atopic features, although no phenotype/genotype correlation was established.
July 2025 in “Medical Science” This review discusses recent studies on the hepatotoxic effects of anabolic androgenic steroids and selective androgen receptor modulators, including liver damage, tumors, and related conditions, and reports no new primary research results.
April 2025 in “Sabuncuoglu Serefeddin Health Sciences” This study highlights the public health significance of androgenic-anabolic steroid use disorder, emphasizing health risks, societal effects, and the need for routine AAS analyses in forensic autopsies, especially in athlete deaths.
39 citations
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April 2007 in “Therapeutic Drug Monitoring” This study found that finasteride significantly alters urinary steroid profiles, complicating the detection of steroid abuse in doping-control analysis by potentially causing false-negative results.
1 citations
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December 2024 in “Journal of Education Health and Sport” In this review, anabolic steroid use was reported to increase risks such as cardiovascular issues, liver damage, endocrine disruptions, and musculoskeletal injuries, with psychological impacts also noted, underscoring the need for education and preventive strategies.
August 2023 in “Medicina-lithuania” This review discusses the degenerative effects of anabolic-androgenic steroids on the nervous system and reports no new experimental results, aiming to increase public awareness of their health risks.
This source offers an in-depth review of Methandrostenolone, examining its pharmacology, performance-enhancing effects, potential health risks, and legal status in various countries, while emphasizing the scientific evidence surrounding its use and misuse.
3 citations
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November 2024 in “Saudi Pharmaceutical Journal” This review highlights significant health risks associated with anabolic-androgenic steroid use in women and reports no new research results, emphasizing the need for further understanding of their effects on female physiology.
2 citations
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June 2020 in “AIDS” This case study describes a severe instance of iatrogenic Cushing's syndrome induced by gamma-hydroxybutyric acid, exacerbated by combined use of betamethasone and anabolic steroids, in an HIV-positive patient on cobicistat-containing therapy.
June 2017 in “International Journal of Research in Dermatology” In this study, researchers observed that skin conditions in Timbi are influenced by occupation, literacy, and systemic diseases, with widespread improper steroid use contributing to complications.
January 2026 in “Case Reports in Dermatological Medicine” In this case study, a young female with aseptic and alopecic nodules of the scalp achieved full resolution without recurrence using intralesional steroids.
January 2002 in “映像情報メディア学会技術報告” This study found that 60% of examined prostate tumors had new somatic substitutions in the SRD5A2 gene, affecting enzyme activity and potentially influencing prostate cancer progression.
January 2023 in “Indian journal of pharmacy practice” This study observed that dermoscopic features of skin affected by topical corticosteroids and hydroquinone correlated with histopathological changes, highlighting the importance of awareness regarding their long-term adverse effects.
1 citations
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November 2021 in “Drug Testing and Analysis” This collection from the 2021 Manfred Donike Workshop outlines advancements in doping detection, highlighting new test methods and challenges, with a focus on steroidal substances, peptide hormones, and gene doping analysis.
This review discusses the complex causal relationships between testosterone exposure and various health outcomes, but notes that the studies reviewed show substantial heterogeneity.
73 citations
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April 1999 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study found that the vitamin D-VDR system is crucial for mineral and bone metabolism post-weaning and identified missense mutations in 1alpha-hydroxylase causing type I rickets.
9 citations
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March 2019 in “European Journal of Sport Science” This article discusses laboratory and physical markers that may help detect androgenic anabolic steroid abuse in athletes and reports no new primary research results.
5 citations
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January 2017 in “Biomedical Research-tokyo” This review examines the long-term health risks of anabolic-androgenic steroid abuse in athletes, reporting various physical and psychological side effects without sufficient benefits.
April 2026 in “International Journal of Impotence Research” This review outlines the major health consequences of anabolic-androgenic steroid abuse, with a focus on sexual and reproductive issues, and suggests management prioritizes cessation and relapse prevention due to lack of robust randomized trials.
3 citations
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January 2008 in “Endocrine journal” In this case report, the authors describe a partial androgen insensitivity syndrome patient with a novel AR gene mutation, highlighting challenges in gender assignment decisions for infants with partial AIS.
55 citations
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July 1999 in “Clinics in Sports Medicine” This review discusses recent data on the use of anabolic-androgenic steroids and other steroid compounds and reports no new clinical results.
38 citations
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September 2019 in “Chinese Medical Journal” This review discusses the cardiovascular risks associated with anabolic-androgenic steroid use and reports that, despite known toxic effects, further research is needed to clarify the causality of these risks.
April 2026 in “Journal of Education Health and Sport” In this study, a literature review highlighted that anabolic-androgenic steroid use in physically active men is associated with adverse effects across multiple body systems, including cardiovascular, endocrine, and psychiatric complications, underscoring the need for increased clinical awareness and further research.
451 citations
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March 2005 in “Endocrine Reviews” This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.
81 citations
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July 2008 in “The Journal of Clinical Endocrinology and Metabolism” This study found that cortisone reductase deficiency is caused by inactivating mutations in the H6PD gene, affecting cortisol metabolism by preventing 11β-HSD1 enzyme function.
30 citations
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October 2020 in “Nature Communications” This study provides the first crystal structure of the human SRD5A2 enzyme, revealing key insights into its function and inhibition which may aid future drug development.