research HPV8 E6 Induced STAT3 Activation Leads to Hair Follicle Junctional Zone Keratinocyte Stem Cell Proliferation and Expansion in Actinic Keratoses
HPV8 causes hair follicle stem cells to grow, leading to skin lesions.
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research Scaly Papular Lesions: Treatment and Clinical Course of Actinic Keratosis
Topical imiquimod is as effective as 5-fluorouracil for treating actinic keratosis, with about a 5% risk of it turning into squamous cell carcinoma.
research Aggressive Squamous Cell Carcinomas of the Scalp
Some aggressive scalp cancers are hard to treat and can be deadly, even when removed with specialized surgery.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor Alpha Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research HPV8 E6 Leads to Lrig1+ Keratinocyte Stem Cell Expansion
HPV8 E6 gene causes growth of certain skin stem cells.
research Malignant Epithelial Tumors: Part II. Therapy and Prevention
The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.
research Neutrophil Gelatinase-Associated Lipocalin Is a Marker for Dysregulated Keratinocyte Differentiation in Human Skin
NGAL indicates abnormal skin cell differentiation.
research Oncogenic Kras Induces Spatiotemporally Specific Tissue Deformation Through Converting Pulsatile Into Sustained ERK Activation
The Kras mutation changes normal cell signals, leading to disrupted tissue structure and potential cancer.
research Oncogenic Ras Mutation Induces Spatiotemporally Specific Tissue Deformation Through Converting Fluctuated Into Sustained ERK Activation
A specific mutation in Kras causes abnormal tissue changes by making a cell signal continuously active, which disrupts normal cell coordination.
research Cutaneous Manifestations of Dabrafenib: A Selective Inhibitor of Mutant BRAF in Patients with Metastatic Melanoma
Dabrafenib can cause skin growths and sometimes low-grade skin cancer.
research Adverse Effects of Voriconazole: Over a Decade of Use
Voriconazole can cause serious side effects, especially in long-term use.
research Docetaxel, Cisplatin and 5-Fluorouracil in Patients with Locally Advanced Unresectable Head and Neck Cancer: A Phase I-II Feasibility Study
The treatment combining docetaxel, cisplatin, and 5-FU is feasible and effective for advanced head and neck cancer.
research Widespread Porokeratotic Adnexal Ostial Nevus: Clinical Features and Proposal of a New Name Unifying Porokeratotic Eccrine Ostial and Dermal Duct Nevus and Porokeratotic Eccrine and Hair Follicle Nevus
The term "porokeratotic adnexal ostial nevus" is proposed to unify overlapping skin conditions involving eccrine and hair follicles.
research Cutaneous Adverse Effects of BRAF Inhibitors in Metastatic Malignant Melanoma: A Prospective Study in 20 Patients
BRAF inhibitors for melanoma often cause skin side effects, but they can be managed with proper care.
research Erosive Pustular Dermatosis of the Scalp: A Neutrophilic Folliculitis Within the Spectrum of Neutrophilic Dermatoses
Erosive pustular dermatosis of the scalp is a type of skin inflammation often confused with other conditions, requiring continuous treatment.
research Cutaneous Toxicities of New Treatments for Melanoma
New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.
research New Developments in Occupational Dermatology
Germany recognizes skin cancer from UV exposure as an occupational disease, emphasizing prevention and care for affected workers.
research Male Pattern Baldness and Risk of Incident Skin Cancer in a Cohort of Men
Men with male pattern baldness have a higher risk of certain skin cancers, especially on the scalp.
research Dermoscopy of Cutaneous Adnexal Tumors: A Systematic Review of the Literature
Most cutaneous adnexal tumors examined were benign and resembled common skin tumors.
research Profile Analysis of Adverse Events After Boron Neutron Capture Therapy for Head and Neck Cancer: A Sub-Analysis of the JHN002 Study
Boron neutron capture therapy for head and neck cancer can cause side effects like mouth sores and skin irritation, which vary depending on where the treatment is aimed.
research Correction: RASopathic Skin Eruptions During Vemurafenib Therapy
Vemurafenib causes significant skin side effects, requiring regular dermatologist care and sun protection.
research Alopecia: The Case for Medical Necessity
Alopecia should be treated as a medical condition because it may increase the risk of serious diseases and psychological issues.
research Usefulness of Dermoscopy to Provide Accurate Assessment of Skin Cancers
Dermoscopy is an effective tool for accurately detecting skin cancers.
research Optimal Placement of Burow's Triangles for Aesthetically Pleasing Repair of Multiple Defects Using Local Flaps After Tumor Excision
The technique effectively repairs skin after tumor removal, maintaining appearance and function without complications.
research Prioritizing Dermatoses: Rationally Selecting Guideline Topics
Dutch dermatologists prioritized skin conditions like melanoma and psoriasis for guideline development, focusing on consistent care over cost or death rates.
research Chronic Crusted Scalp Lesion of an Elderly Male
An elderly man's non-healing scalp lesion was successfully treated with a strong topical steroid.
research Dermatologic Care of the Transplant Patient
Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.
research Advancements and Challenges in Hair Transplantation Surgery
The article concludes that hair transplantation is advancing, but a reliable way to ensure complete tumor removal is still needed.
research Diuretics
Diuretics can cause serious side effects and should be used carefully.
research Use of Ultra-Fast One-Step CK5 IHC for Identifying BCC and SCC During Mohs Surgery
A new one-step test can quickly identify skin cancer during surgery.