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In this study, a subcutaneous injection of recombinant RSPO1 was found to activate hair follicle stem cells and enhance hair regeneration in mice by stimulating the Wnt/β-catenin signaling pathway, suggesting its potential as a treatment for hair loss.

This study found that after 12 weeks of taking the trial product SHPro®, participants reported improvements in prostate symptom scores and erectile function, with confirmed safety.

Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.

This report describes a case of a patient with Sjogren's syndrome who experienced multiple episodes of aseptic meningitis linked to taking trimethoprim-sulfamethoxazole and trimethoprim alone.

CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.

This study found that the wavy coat trait in Nakano cataract mice is polygenic, involving major and minor genes, and resembles human curly scalp hair associated with the PRSS53 gene alteration.

This case report describes a patient who developed Trichodysplasia spinulosa, a folliculocentric viral infection, after heart transplantation, and experienced improvement in her skin condition following modulation of immunosuppressive therapy and application of topical cidofovir.

ASLAN004 was safe and well-tolerated, supporting further development for treating certain diseases.

Reduced TRPS1 leads to increased STAT3 and SOX9 in hair follicles, affecting hair growth.

In this study, a child's diagnosis of Silver-Russell syndrome was confirmed through phenotype data, genetic testing, and the exclusion of other developmental conditions, revealing a need for a multidisciplinary care approach.

This study identified ISPP-Rb, a novel immuno-stimulatory complex from Royoporus badius, that significantly activates murine macrophage cells and induces multiple proinflammatory cytokines.

This study found that Polycomb Repressive Complex 1 is crucial for maintaining stem cell identity across different lineages, but its loss results in varied transcriptional outcomes depending on the tissue context.

In this study, gel containing apigenin and celery herb extract was observed to effectively stimulate hair growth and did not cause skin irritation in male Sprague-Dawley rats.

This study demonstrated that in genetic mouse models, the calcium sensor Stim1, not Stim2, is essential for sweat secretion in sweat glands.

This study concluded that the Scalp Photographic Index is a reliable and validated tool for objectively classifying and scoring various scalp conditions.

This study found that mimicking the XPD point mutation in mice resulted in trichothiodystrophy-like symptoms, supporting the role of basal transcription and DNA repair defects in the disease.

The Celsr1 gene is crucial for normal hair patterning in mice.

This case report identifies a novel mutation in a patient with trichorhinophalangeal syndrome 1 and reduced TRPS 1 protein expression in hair follicle tissues compared to normal subjects.

This study found that knocking out the transactivation domain of Miz1 in mouse keratinocytes disrupted hair follicle orientation, caused irregular pigmentation, and increased keratinocyte proliferation, indicating Miz1's role in hair follicle development and morphogenesis.

In this study, researchers found that the SLICK1 allele in cattle may alter local immune regulation, hair growth, and tissue remodeling, as indicated by differential gene expression pathways associated with immune and inflammatory responses in slick vs. nonslick Holsteins.

This article discusses the use of Espumil foam base in pharmacies for preparing dermatological medications and reports no new clinical results.

In this study using Xenopus laevis embryos, reduced levels of the desmosomal protein desmoplakin led to defects in epidermal and cardiac structures, suggesting its crucial role in tissue integrity.

INTASYL is a promising, adaptable RNAi technology for treating skin cancers.

This study describes unique anatomical characteristics of the skin and hair structures in the silver marmoset, including features such as thin epidermis, specialized nerve end-organs, and distinctive gland compositions.