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Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

A new mutation in the ST14 gene broadens the understanding of ichthyosis-hypotrichosis syndrome.

Docetaxel and paclitaxel for breast cancer can cause permanent, severe hair loss.

A defective protein in progeria causes cell death and atherosclerosis, but a treatment targeting cell stress may reduce these effects.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Low TRPS1 expression in skin and hair cells is linked to hair problems in Trichorhinophalangeal syndrome.

Hutchinson-Gilford Progeria Syndrome is a rare genetic disorder caused by a specific gene mutation, characterized by aging symptoms and managed by monitoring heart health and using low-dose aspirin.

A new gene variant causes glucocorticoid resistance in a mother and son.

Patients with Systemic Sclerosis have much higher levels of GDF-15, which could help predict organ involvement and guide treatment.

Some Greek melanoma patients have gene mutations linked to increased cancer risk, a new color feature helps diagnose melanoma, the incidence of a skin condition in the Netherlands is rare, and a gene possibly affects male-pattern baldness.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

The boy's severe skin disorder is caused by two new mutations in his TGM1 gene.

A new gene mutation causes insulin resistance in a girl and her mother.

Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.

K6hf is a unique protein found only in a specific layer of hair follicles.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

FOXN1 gene variants cause low T cells and immune issues from birth.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.