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Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.

Two new compounds were found to effectively reduce hair growth in mice.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The study found genetic differences related to hair development that may explain hair loss in a patient with Trichorhinophalangeal syndrome type I.

New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.

Targeting the Smoothened receptor shows promise for treating certain cancers.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

The hedgehog signalling pathway is key in skin development and basal cell carcinoma, offering insights for prevention and treatment.

Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.

Cells from certain embryo parts can induce head formation in another embryo, involving complex signaling pathways.

The method quickly analyzes hair growth genes and shows that blocking Smo in skin cells stops hair growth.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

The treatment was ineffective in humans.

Applying a special compound can promote hair growth without harmful side effects.

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

The research suggests new treatments for skin cancer could target specific cell growth pathways.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

Effective PCOS treatments require targeting specific signaling pathways.

Light can turn on hair growth cells through a nerve path starting in the eyes.

Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.