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Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

Cannabinoids may help treat various skin conditions.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Inactive hair follicle stem cells help prevent skin cancer.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Apoptosis is crucial for healthy skin and treating skin diseases.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Vitamin D and its receptor may help prevent skin cancer.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Vitamin D receptor may help protect against UV-induced skin cancer.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Combining irinotecan and cetuximab is effective for some metastatic colorectal cancer patients but often causes manageable skin issues.

Nasolabial skin-fat grafts are good for nasal reconstruction with minimal scarring and no need for bolsters, but smoking may affect graft survival.