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      Is COVID-19 Gender-Sensitive?

      research Is COVID-19 Gender-sensitive?

      228 citations , January 2021 in “Journal of Neuroimmune Pharmacology”
      This review explores possible reasons for why male COVID-19 patients experience more severe symptoms and higher fatality rates than female patients but provides no new clinical results.
      Eph Receptors and Ephrins: Therapeutic Opportunities

      research Eph Receptors and Ephrins: Therapeutic Opportunities

      222 citations , October 2014 in “Annual Review of Pharmacology and Toxicology”
      This review discusses the roles of Eph receptors and ephrins in various diseases, highlighting their potential as therapeutic targets, but it presents no new research findings.
      A Guide to Studying Human Hair Follicle Cycling In Vivo

      research A Guide to Studying Human Hair Follicle Cycling In Vivo

      212 citations , September 2015 in “Journal of Investigative Dermatology”
      This article presents a comprehensive guide for classifying human hair follicle cycle stages in vivo using scalp xenografts on immunocompromised mice, offering valuable resources for researchers in the field.
      Alopecia Areata: A Review of Disease Pathogenesis

      research Alopecia areata: a review of disease pathogenesis

      191 citations , May 2018 in “British journal of dermatology/British journal of dermatology, Supplement”
      This study reviewed recent theories on alopecia areata's pathogenesis, highlighting its autoimmune nature due to immune privilege disruption in hair follicles, and noted current treatments have limited efficacy with high relapse rates, underscoring the need for further research into its mechanisms for better therapies.
      Adverse Effects of Opioid Analgesic Drugs

      research ADVERSE EFFECTS OF OPIOID ANALGESIC DRUGS

      183 citations , January 1987 in “British Journal of Anaesthesia”
      This article discusses the long-standing use and safety of opioids in anaesthesia, noting that respiratory depression is a manageable side effect due to the availability of opioid antagonists.
      Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions

      research Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions

      178 citations , August 2016 in “Advances in wound care”
      This article discusses advancements in understanding how skin stem cells and fibroblasts contribute to scar formation, highlighting current and potential therapies aimed at preventing or reducing scarring, yet notes that effective treatments without significant side effects are still lacking.
      Low-Level Laser Therapy for Treatment of Hair Loss

      research Low‐level laser (light) therapy (LLLT) for treatment of hair loss

      165 citations , August 2013 in “Lasers in Surgery and Medicine”
      This review discusses the potential mechanisms and evidence supporting low-level laser therapy for stimulating hair growth in men and women, while noting its safety and effectiveness but needing further study on specific parameters.
      The Hair Follicle as an Estrogen Target and Source

      research The Hair Follicle as an Estrogen Target and Source

      159 citations , July 2006 in “Endocrine Reviews”
      This article discusses the influence of estrogens on hair follicle growth and metabolism, suggesting a significant role alongside androgens in hair growth control but reports no new clinical results.
      AXR3 and SHY2 Interact to Regulate Root Hair Development

      research AXR3andSHY2interact to regulate root hair development

      157 citations , October 2003 in “Development”
      This study found that different stabilizing mutations in Aux/IAA proteins affect root hair development in Arabidopsis by disrupting the auxin response and suggest a model where the relative abundance of these proteins determines root hair initiation.
      Androgenetic Alopecia: A Review

      research Androgenetic alopecia: a review

      153 citations , March 2017 in “Endocrine”
      This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.
      Gender Differences in Skin: A Review of the Literature

      research Gender differences in skin: A review of the literature

      152 citations , December 2007 in “Gender Medicine”
      This review discusses recent advances in understanding gender differences in skin and their implications for dermatologic diseases, but it reports no new experimental results; ongoing research is necessary for translating these insights into clinical practice.
      Cutaneous Lupus Erythematosus: A Review

      research Cutaneous lupus erythematosus: a review

      149 citations , July 2002 in “Dermatologic clinics”
      This review discusses the pathogenesis, clinical presentation, diagnosis, and treatment of cutaneous lupus erythematosus, reporting no new clinical findings.
      WNT Signaling in Disease

      research WNT Signaling in Disease

      144 citations , August 2019 in “Cells”
      This review discusses the WNT signaling pathway's involvement in human diseases and highlights recent advances in WNT-related treatments, but it presents no new research findings.
      Generalized Pustular Psoriasis: A 29-Year Study of 63 Patients

      research Generalized Pustular Psoriasis

      143 citations , September 1991 in “Archives of Dermatology”
      In this study, patients with generalized pustular psoriasis were classified into subgroups to better understand the disease's variability and assist in treatment selection, highlighting the role of localized infections in triggering flares.
      Molecular Mechanisms of Viral Oncogenesis in Humans

      research Molecular mechanisms of viral oncogenesis in humans

      141 citations , August 2018 in “Nature Reviews Microbiology”
      This review discusses the molecular mechanisms by which oncogenic viruses contribute to cancer development through manipulation of host cellular functions and highlights the need for further research into virus-associated cancers, reporting no new results.
      Transfollicular Drug Delivery: Is It a Reality?

      research Transfollicular drug delivery—Is it a reality?

      141 citations , November 2005 in “International journal of pharmaceutics”
      This review examines the role of hair follicles and sebaceous glands in percutaneous drug delivery but does not report new clinical results; it calls for further exploration of follicle-targeting therapies.
      Microneedles as the Technique of Drug Delivery Enhancement in Diverse Organs and Tissues

      research Microneedles as the technique of drug delivery enhancement in diverse organs and tissues

      140 citations , December 2017 in “Journal of Controlled Release”
      This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.
      Do Men's Faces Really Signal Heritable Immunocompetence?

      research Do men’s faces really signal heritable immunocompetence?

      138 citations , October 2012 in “Behavioral Ecology”
      This review argues that the immunocompetence hypothesis, linking masculine facial features to attractiveness through health benefits, lacks sufficient evidence and sidesteps alternative explanations.