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The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Sex hormones might influence bladder cancer development, and aromatase inhibitors could increase risk in postmenopausal women.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.

Lower SHBG levels may increase the risk of PCOS.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.