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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Finasteride may cause long-lasting sexual side effects.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.

New compounds may soon be tested to treat excessive hair growth in women.

Bald men are not more virile and may have fewer sexual partners.

Most European physicians know the risks and safe use of Cyproterone acetate, but few remember receiving official safety communications.

Trazodone and chlorpromazine may help treat sexual dysfunction caused by finasteride and SSRIs.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Finasteride can cause sexual problems and depression in young men.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.

Finasteride side effects in young men may be linked to specific gene variations.

Polycystic Ovary Syndrome (PCOS) symptoms vary globally, with bloating, high cholesterol, and glucose levels being common; the current diagnostic criteria may need refining.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Dutasteride 0.5 mg daily improves hair growth safely in men with hair loss.

Muscles and nerves that cause goosebumps also help control hair growth.