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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Most women with PCOS have high levels of male hormones, and free testosterone is the best marker for this.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.