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Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Different types of skin cells play specific roles in development, healing, and cancer.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Sebocytes play a key role in controlling androgen levels in human skin.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Trichoscopy is a useful tool for diagnosing different hair and scalp diseases by their unique visual features.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Zinc is effective for treating various skin conditions, including warts and acne.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Accurate diagnosis and effective oral treatment are key to managing tinea capitis and preventing its spread.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Scalp dermoscopy is good for diagnosing a type of hair loss and helps choose the best spots for biopsy.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Cathepsin L is essential for normal hair growth and development.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Too much androgen can cause hair loss; finasteride may help.