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Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

Aging causes skin stem cells to work less effectively.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Targeting hair follicles can improve skin treatments and reduce side effects.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Vitamin D3 affects cell differentiation in specific skin areas.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

Prostaglandin D₂ might be targeted for new male pattern baldness treatments.

Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.

Children's hair grows in different types from before birth through puberty, with growth rates and characteristics varying by age, sex, and race.

Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.

Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.