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    Glossary Scar Tissue

    fibrous tissue replacing normal skin after injury or surgery

    Scar tissue, also known as cicatrix, is the fibrous connective tissue that forms over a wound as it heals. Unlike normal skin, scar tissue is composed primarily of collagen and lacks the full functionality and appearance of the original tissue, often resulting in a different texture and color. This tissue can form after injuries, surgeries, or conditions like severe acne, and while it serves to protect the wound, it can sometimes lead to complications such as restricted movement or discomfort.

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    1. Hair Follicle Transplantation on Scar Tissue Journal of Craniofacial Surgery · 2013 · 28 citations
    2. Staged Hair Transplantation in Face and Scalp Scars after Carbon Dioxide Laser or Platelets Rich Plasma-Assisted Scar Tissue Remodeling The Egyptian Journal of Hospital Medicine · 2025
    3. Scar Tissue Grafting Dermatologic Surgery · 1998
    4. Tissue Expansion and Serial Excision in Scar Revision Facial Plastic Surgery · 2001 · 25 citations
    5. Recent Advances in Wound Healing, Tissue Repair, Regeneration and Scar Management Preprints.org · 2026
    6. Tissue engineering in burn scar reconstruction Burns & Trauma · 2015 · 41 citations
    7. Regeneration of Human Scar Tissue with Topical Iodine: A Preliminary Report—Part 2 2008 · 1 citations
    8. LB1027 Identifying the mechanism of tension-associated tissue fibrosis based on single cell RNA sequencing on keloid scar Journal of Investigative Dermatology · 2024
    9. 3D white light interferometry assessment of robotic laser scalpel assisted surgery to minimise scar tissue formation International Journal of Surgery · 2016 · 2 citations
    10. Systematic review of the therapeutic roles of adipose tissue in dermatology Journal of The American Academy of Dermatology · 2018 · 18 citations
    11. Design of an artificial skin. IV. Use of island graft to isolate organ regeneration from scar synthesis and other processes leading to skin wound closure Journal of Biomedical Materials Research · 1998 · 13 citations
    12. Hair transplantation in burn scar alopecia Scars, burns & healing · 2015 · 8 citations
    13. Anagen hair follicles transplanted into mature human scars remodel fibrotic tissue npj regenerative medicine · 2023 · 6 citations
    14. Transcription factor c‐Maf drives macrophages to promote hypertrophic scar formation Journal of Cosmetic Dermatology · 2023 · 5 citations
    15. Clinical Efficacy and Safety of Pulsed Dye Laser Combined with Pingyangmycin on Hyperplastic Scar after Acne Mediators of Inflammation · 2022 · 5 citations
    16. Hair follicle-inspired therapies for wound healing and scar remodelling Journal of Plastic Reconstructive & Aesthetic Surgery · 2025 · 2 citations
    17. Cell-free adipose extract inhibits hypertrophic scar formation through collagen remodeling and antiangiogenesis Open Medicine · 2025
    18. Commentary on: Hair Transplantation in Burn Scar Alopecia After Combined Non-Ablative Fractional Laser and Microfat Graft Treatment Aesthetic Surgery Journal · 2021
    19. Bioactive Glasses: Advancing Skin Tissue Repair through Multifunctional Mechanisms and Innovations Biomaterials Research · 2025 · 14 citations
    20. Gallic Acid Nanocrystal Hydrogel: A Novel Strategy for Promoting Wound Healing and Inhibiting Scar Formation International Journal of Nanomedicine · 2025 · 13 citations
    21. Regenerative Cosmetics: Skin Tissue Engineering for Anti-Aging, Repair, and Hair Restoration 2024 · 1 citations
    22. Skin wounds in the MRL/MPJ mouse heal with scar Wound Repair and Regeneration · 2006 · 51 citations
    23. Treatment of Postsurgical Scalp Scar Deformity Using Follicular Unit Hair Transplantation BioMed Research International · 2019 · 11 citations
    24. Effects of ginsenoside Rb1 on hypertrophic scar remodeling in rabbit model European journal of pharmacology · 2015 · 10 citations
    25. Scar Inhibition in Wound Healing: Mechanisms, Design, and Recent Advances Exploration · 2026
    26. Tissue engineering strategies combining molecular targets against inflammation and fibrosis, and umbilical cord blood stem cells to improve hampered muscle and skin regeneration following cleft repair Medicinal Research Reviews · 2019 · 30 citations
    27. An Assessment of Quality-of-Life Following Tissue Expansion in Pediatric Patients Plastic Surgery · 2023 · 1 citations
    28. [Effect of deep dermal tissue dislocation injury on skin fibrosis in pig]. PubMed · 2022
    29. From Design to Production: Applications of Polymer and Protein Nanofibers for Regenerating Tissue Digital Access to Scholarship at Harvard (DASH) (Harvard University) · 2018
    30. Treatment of a Spinal Cord Hemitransection Injury with Keratin Biomaterial Hydrogel Elicits Recovery and Tissue Repair ISRN Biomaterials · 2014 · 7 citations