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Glossary Keloid Scarring

overgrowth of dense, fibrous tissue extending beyond original wound

Keloid scarring refers to an overgrowth of dense, fibrous tissue that extends beyond the original wound boundaries, forming a raised, thickened scar. Unlike regular scars, keloids do not regress over time and can continue to grow, often causing discomfort or cosmetic concerns. They are more common in individuals with darker skin tones and can result from various skin injuries, including cuts, burns, or surgical incisions.

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Research

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research Gut microbiota-derived metabolites in keloid and hypertrophic scarring

3 citations , September 2025 in “Frontiers in Microbiology”

This review article proposes a possible skin-gut-fibrosis axis, suggesting that gut microbial metabolites may influence the development of keloids and hypertrophic scars by affecting immune responses and fibrotic signaling pathways, although direct evidence in skin fibrosis remains limited.

research Toward understanding scarless skin wound healing and pathological scarring

113 citations , June 2019 in “F1000Research”

This review discusses the mechanisms of wound healing and excessive scarring, highlighting the importance of understanding these processes for developing new therapies to prevent fibrotic scarring in large skin wounds.

research Follicular and Scarring Disorders in Skin of Color: Presentation and Management

30 citations , May 2014 in “American Journal of Clinical Dermatology”

This review discusses follicular and scarring disorders in skin of color and highlights the need for patient education and tailored therapeutic strategies, but does not report new clinical findings.

research Fibroblasts become fat to reduce scarring

13 citations , February 2017 in “Science”

Turning scar-forming cells into fat cells can reduce scarring.

research Potential genetic associations of acne scar phenotypes: IL1A in fibrotic scarring and CYB5R1 in atrophic scarring

April 2026 in “Biomedical Research and Therapy”

This study found that certain genetic variants, specifically CYB5R1 and IL1A, may be linked to different types of acne scarring, with CYB5R1 associated with atrophic scarring and IL1A with fibrotic scarring, indicating a potential polygenic nature of acne scarring.

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Learn

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learn Scalp Micropigmentation

Can scalp micropigmentation hide my scars? Scalp micropigmentation can significantly reduce the visibility of scars on the scalp.
Who cannot get scalp micropigmentation? Individuals with active skin conditions, keloid scarring, or certain medical issues should avoid SMP.

learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth

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Community Join

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community Are Derma Rollers Actually Harmful in the Long Run?

in Microneedling 40 upvotes 1 year ago

Derma rollers may cause scarring alopecia, leading some to prefer dermastamps or dermapens for microneedling. Combining minoxidil with microneedling is effective, but proper technique and healing time are essential to prevent damage.

community Why is my dermatologist strictly against derma stamping/derma rolling?

in Microneedling 27 upvotes 1 year ago

Dermatologists often advise against at-home microneedling due to risks of scarring, infection, and improper technique. Professional guidance is recommended for safe and effective use, with some users reporting positive results when done correctly.

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Clinics

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36
Hair Loss Treatments
Rejuvence Skin & Hair Clinic - Keloid & Scar SpecialistLondon, England · GB

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