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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Different types of skin cells play specific roles in development, healing, and cancer.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Noggin is necessary to start the hair growth phase in skin after birth.

Lactate production is important for activating hair growth stem cells.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Sebocytes play a key role in controlling androgen levels in human skin.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.