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New retinoids are effective for various skin conditions and are being developed to have fewer side effects.

This study found that SMR-2 and SMR-6, analogs of retinoic acid and retinol, were approximately 100 times more toxic than retinoic acid in mice, inducing hypervitaminosis A and affecting various organs and tissues.

This article reviews the current status of oral retinoids in dermatology and reports no new clinical findings.

This review discusses the potential benefits of nonantibiotic macrolides for treating inflammatory skin disorders and reports no new clinical results.

This report verifies isotretinoin's significant efficacy in treating severe acne over the past year in the U.S., highlighting the need for careful patient selection and monitoring due to potential side effects.

This study reported that clascoterone cream reduced inflammatory and noninflammatory acne lesions in a trial with 1440 white males and non-pregnant females, showing it was well tolerated in these participants.

Retinoids are effective for acne but can cause serious side effects.

This study found that patients with rheumatoid arthritis who discontinued and restarted methotrexate had less improvement in disease activity, more side effects, and more initial comorbidities than those who persisted on the therapy.

Some medications and supplements can cause serious side effects, including hair loss, heart rhythm problems, liver injury, and other health issues.

This study found that oral isotretinoin may slightly improve physician-assessed acne severity but is associated with more minor adverse effects compared to standard oral antibiotics plus topical treatment, based on low-quality evidence.

This article reviews the clinical efficacy of Ruxolitinib cream for skin conditions, reporting significant improvements in atopic dermatitis and vitiligo, with minimal systemic absorption and a favorable safety profile, compared to placebo.

Acne treatment, including isotretinoin, improves quality of life and does not worsen depression.

This report describes cases of transient thyrotoxicosis potentially linked to oral retinoid treatment, suggesting a possible mechanism involving increased iodine uptake by thyroid cells.

This report describes a case of a 19-year-old woman experiencing severe recurrent angioedema with airway issues, leading to multiple emergency visits and unsuccessful treatment with typical steroid-sparing agents.

This review provides guidelines for physicians on using hormonal therapies, such as androgen receptor blockers and oral contraceptives, to treat hormonally related acne, but reports no new clinical findings.

In this study, researchers reported that the Pinkie mutation in mice, affecting RXRa activity, leads to skewed Th1 development and suggests RXRa's role in Th2 differentiation, impacting immune responses.

This review discusses the properties and applications of doxycycline in dermatology and reports no new clinical results, emphasizing its potential for treating various dermatological conditions.

This article reviews various updates in dermatology, including drug safety alerts and treatment options, and reports no new clinical results.

In this study, oral etretinate resulted in increased hair length and loss of beading in a childhood monilethrix case, while the scalp's keratosis pilaris persisted.

This synthesis report details the successful development of a C-14 labeled isotopomer of LY300502, a 5α-reductase inhibitor, through a multi-step radiochemical process.

This study reported that BRL 7660 significantly reduced sebum secretion and acne symptoms in human studies with topical administration, but the placebo effect and commercial pressures halted further investigations.

This article discusses the rising use of low-dose oral minoxidil for androgenetic alopecia and mentions common side effects like hypertrichosis, but provides no new clinical findings.

In this study, common side effects of isotretinoin, including dry lips, mucous membrane dryness, tiredness, and mood changes, were frequently reported among Polish patients, though their severity was usually mild.

In this study, researchers validated a computational workflow for repurposing non-antibacterial drugs as antibacterial agents and highlighted daprodustat, combined with an efflux pump inhibitor, as a promising strategy against bacterial pathogens.

This study reported that a 1% ivermectin topical cream for rosacea was stable over six months, showing no significant changes in key physical properties or microbial contamination, suggesting it may reduce chronic antibiotic use in rosacea treatment.

This study found that ion-paired solutions significantly improved the skin penetration of risedronate in hairless mice compared to risedronate alone.

This case report describes the successful treatment of a 13-year-old girl's autoimmune symptoms with co-trimoxazole, an antibiotic with immunomodulatory properties.