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Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Sebocytes play a key role in controlling androgen levels in human skin.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Sulforaphane from broccoli can help protect skin from sun damage.

Fibrinogen/LDL apheresis may improve speech perception in sudden hearing loss, especially for those with high fibrinogen and LDL levels.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Latanoprost can make eyelashes longer, thicker, and darker.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.

Accurate diagnosis and effective oral treatment are key to managing tinea capitis and preventing its spread.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Superficial granulomatous pyoderma is a unique, mild form of skin disease that often heals without strong medication and responds well to milder treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.